Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,973 questions · 3,072 findings · 410 reviews · Headline outcomes only

No studies found 559 · 18.2%GRADE not reported 143 · 4.7%Very low 654 · 21.3%Low 833 · 27.1%Moderate 683 · 22.2%High 200 · 6.5%

Intervention not reported

Incidence of bronchopulmonary dysplasia · preterm infants less than 30 weeks' gestational age requiring conventional mechanical ventilation for respiratory distress syndrome

The intervention showed no clear difference in incidence of bronchopulmonary dysplasia (low certainty).

1 finding from 1 review

Surfactant administration via thin catheter (S‐TC) vs surfactant administration through an endotracheal tube (S‐ETT)

Death or bronchopulmonary dysplasia at 36 weeks PMA · preterm infants with or at risk of respiratory distress syndrome

Surfactant administration via thin catheter (S‐TC) probably leads to lower death or bronchopulmonary dysplasia (BPD) at 36 weeks' postmenstrual… compared with surfactant administration through an endotracheal tube (S‐ETT) (moderate certainty).

1 finding from 1 review

Surfactant administration via thin catheter (S‐TC) vs surfactant administration through an endotracheal tube (S‐ETT)

Bronchopulmonary dysplasia · preterm infants with or at risk of respiratory distress syndrome

Surfactant administration via thin catheter (S‐TC) probably leads to lower bronchopulmonary dysplasia (BPD) among survivors at 36 weeks'… compared with surfactant administration through an endotracheal tube (S‐ETT) (moderate certainty).

1 finding from 1 review

Tracheal suction vs no tracheal suction

Persistent pulmonary hypertension · non‐vigorous neonates born through meconium‐stained amniotic fluid

It is very uncertain whether tracheal suction changes persistent pulmonary hypertension (PPHN) compared with no tracheal suction (very low certainty).

1 finding from 1 review

Intervention not reported

PUL (UroLift) (mixed estimate) · men with moderate to severe lower urinary symptoms due to benign prostatic hyperplasia Interventions: minimally invasive treatments.…

It is very uncertain whether the intervention changes PUL (UroLift) (mixed estimate) (very low certainty).

1 finding from 1 review

Exercise vs no exercise

Pulmonary complications (0 to 30 days) · adults with clinically diagnosed AAA deemed suitable for elective repair

It is very uncertain whether exercise changes perioperative and postoperative complications: pulmonary complications compared with no exercise (very low certainty).

1 finding from 1 review