Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

613 questions · 624 findings · 42 reviews · Headline outcomes only

No studies found 85 · 13.6%GRADE not reported 37 · 5.9%Very low 211 · 33.8%Low 181 · 29%Moderate 92 · 14.7%High 18 · 2.9%

Second generation antidepressant vs placebo medication

Remission or response (as defined in trial) · patients with depressive disorders in children and adolescents

Second generation antidepressant probably leads to higher remission or response (as defined in trial) compared with placebo (by medication) (moderate certainty).

1 finding from 1 review

Second generation antidepressant vs placebo medication

Suicide‐related outcomes Timing of outcome assessment: end of treatment (6 to 12 weeks treatment duration) · patients with depressive disorders in children and adolescents

Second generation antidepressant may leads to higher suicide‐related outcome compared with placebo (by medication) (low certainty).

1 finding from 1 review