Tricyclic antidepressants vs control: Withdrawals due to adverse events
- Population
- patients with pain management in rheumatoid arthritis
- Intervention
- Tricyclic antidepressants
- Comparison
- control
- Outcome
- Withdrawals due to adverse events
It is very uncertain whether tricyclic antidepressant changes number of Withdrawals due to Adverse Events patient interview compared with control (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Tricyclic antidepressant vs control Number of Withdrawals due to Adverse Events patient interview · patients with pain management in RA It is very uncertain whether tricyclic antidepressant changes number of Withdrawals due to Adverse Events patient interview compared with control (very low certainty). Antidepressants for pain management in rheumatoid arthritis (2011) · Cochrane Headline outcomes only | RR 0.98 [0.59, 1.64] | 6 studies · 455 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Antidepressants for pain management in rheumatoid arthritis 2011 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
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- Tricyclic antidepressants vs placebo · somatoform disorders in adults · 1 review
- Tricyclic antidepressants vs placebo · adults with panic disorder · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.