Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

418 questions · 611 findings · 68 reviews

No studies found 88 · 14.4%GRADE not reported 237 · 38.8%Very low 74 · 12.1%Low 115 · 18.8%Moderate 87 · 14.2%High 10 · 1.6%

Intervention not reported

There was no evidence of differences in the number of serious adverse events for any of the comparisons Quality of evidence = very low1,2,3. · people undergoing liver resection

The review found no eligible studies for this question.

1 finding from 1 review

Lower vs higher oxygen concentrations titrated to target oxygen saturations during resuscitation of preterm infants at birth

Intubation in the delivery room · preterm infants

Lower showed no clear difference in intubation in the delivery room compared with higher oxygen concentrations titrated to target oxygen saturations… (low certainty).

1 finding from 1 review

Primary dental health aide (PDHA) service-delivery models (PDHA program; PDHA + intensive staffing; PDHA + robust prevention) vs Baseline pre-intervention service-delivery scenario

Projected mean DMFT (children below 5 years) · Alaska Native children (below age 18)

A simulation projected mean DMFT in children under 5 would fall from 7.4 to 4.9 under the PDHA model (certainty not graded).

1 finding from 1 review

Lower genital tract infection screening vs No screening

Preterm low birthweight (below or equal 2500 g) · pregnant women presenting for routine prenatal care

Lower genital tract infection screening probably leads to lower preterm low birthweight (below or equal 2500 g) compared with no screening (moderate certainty).

1 finding from 1 review

Planned early birth vs expectant management

Major neonatal morbidity · pregnant women with a term suspected compromised baby

Planned early delivery showed no clear difference in major neonatal morbidity one or more of the following: hypoxic… compared with expectant management (low certainty).

1 finding from 1 review

Planned early birth vs expectant management

Significant maternal morbidity one or more of the following: significant postpartum haemorrhage requiring blood transfusion; maternal admission to intensive care unit; uterine rupture; hysterectomy · pregnant women with a term suspected compromised baby

Planned early delivery showed no clear difference in significant maternal morbidity one or more of the following:… compared with expectant management (low certainty).

1 finding from 1 review

Primary‐level worker‐led collaborative care vs usual care

Prevalence of CMD ‐ intermediate term (1 to 6 months post intervention) Diagnosis defined by presence of ICD‐10 diagnosis on CIS‐Rg; prevalence defined by [Total number ‐ number recovered (recovery defined by HDRS < 8)]c (RR < 1 denotes lower prev... · adults with common mental disorders

Primary‐level worker‐led collaborative care showed no clear difference in prevalence of CMD ‐ intermediate term (1 to 6 months post… compared with usual care (low certainty).

1 finding from 1 review

Low‐cavity forceps vs any vacuum cup

Failed delivery with allocated instrument (primary) · Women in the second stage of labour, requiring an assisted vaginal birth

It is very uncertain whether low‐cavity forceps changes failed delivery with allocated instrument (primary) compared with any vacuum cup (very low certainty).

1 finding from 1 review