Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

331 questions · 353 findings · 56 reviews

No studies found 41 · 11.6%GRADE not reported 74 · 21%Very low 128 · 36.3%Low 66 · 18.7%Moderate 32 · 9.1%High 12 · 3.4%

Intervention not reported

Number of subjects who had one or more exacerbations over the study period in children and adolescents ( · Adults and children with asthma

The intervention showed no clear difference in number of subjects who had one or more exacerbations over the study… (moderate certainty).

1 finding from 1 review

Preformed metal crown (stainless steel), conventional technique vs Aesthetic crown (stainless steel with composite/white veneer), conventional technique

Adverse events: bone resorption · Children with decayed primary molar teeth
1 finding from 1 review
  • Preformed crowns for decayed primary molar teeth 2015 · Cochrane All outcomes
    Six months and four years
    Bone resorption: one case at six months in a tooth treated with a veneer crown; no bone resorption at either the veneer crown or stainless steel sites at four-year follow-up (Analysis 3.2).
    1 study · 11 participants
    Very low

Preformed metal crown (stainless steel), conventional technique vs Aesthetic crown (stainless steel with composite/white veneer), conventional technique

Adverse events: gingival bleeding · Children with decayed primary molar teeth
1 finding from 1 review
  • Preformed crowns for decayed primary molar teeth 2015 · Cochrane All outcomes
    Six months and four years
    At six months, none (0/11) of the PMC sites had gingival bleeding, but all (11/11) veneer sites had bleeding, 10 of which bled on probing; statistically significant (McNemar's test, P < 0.001). At four years, one case…
    1 study · 11 participants
    Very low

Resin composite restorations containing antibacterial agents vs Non-antibacterial containing composite restorations

Secondary caries · Adults and adolescents in any age group with restorations in the permanent dentition and children with restorations in the primary dentition

The review found no eligible studies for this question.

1 finding from 1 review

Resin composite restorations containing antibacterial agents vs Non-antibacterial containing composite restorations

Costs (direct costs of interventions) · Adults and adolescents in any age group with restorations in the permanent dentition and children with restorations in the primary dentition

The review found no eligible studies for this question.

1 finding from 1 review

Resin composite restorations containing antibacterial agents vs Non-antibacterial containing composite restorations

Patient's view and satisfaction with the treatment · Adults and adolescents in any age group with restorations in the permanent dentition and children with restorations in the primary dentition

The review found no eligible studies for this question.

1 finding from 1 review

Resin composite restorations containing antibacterial agents vs Non-antibacterial containing composite restorations

Adverse effects · Adults and adolescents in any age group with restorations in the permanent dentition and children with restorations in the primary dentition

The review found no eligible studies for this question.

1 finding from 1 review

Resin composite restorations containing antibacterial agents vs Non-antibacterial containing composite restorations

Postoperative sensitivity, marginal adaptation, anatomic form and other clinical outcomes (USPHS restoration quality; includes tooth vitality and pulpitis) · Adults and adolescents in any age group with restorations in the permanent dentition and children with restorations in the primary dentition

The review found no eligible studies for this question.

1 finding from 1 review

Resin composite restorations containing antibacterial agents vs Non-antibacterial containing composite restorations

Restoration survival · Adults and adolescents in any age group with restorations in the permanent dentition and children with restorations in the primary dentition

The review found no eligible studies for this question.

1 finding from 1 review

Summary of findings table – disulfiram vs placebo or no pharmacological treatment

Continuous abstinence from cocaine (number of participants who had achieved and maintained abstinence for at least three weeks at the end of treatment) · patients with the treatment of cocaine dependence

Summary of findings table – disulfiram showed no clear difference in continuous abstinence from cocaine (number of participants who had… compared with placebo or no pharmacological treatment (low certainty).

1 finding from 1 review

Intervention not reported

Proportion of patients achieving and maintaining undetectable viral load, e.g. less than 400 copies/ml · HIV infected adults who meet the WHO criteria for commencing antiretroviral treatment.

The intervention may leads to higher proportion of patients achieving and maintaining undetectable viral… (low certainty).

1 finding from 1 review

Intervention not reported

Proportion of patients achieving and maintaining undetectable viral load, e.g. less than 50 copies/ml · HIV infected adults who meet the WHO criteria for commencing antiretroviral treatment.

The intervention may leads to higher proportion of patients achieving and maintaining undetectable viral… (low certainty).

1 finding from 1 review

Triclosan/copolymer-containing fluoride toothpaste vs Fluoride toothpaste without triclosan

Calculus · Children and adults (aged 16 years or less = children, over 16 = adults) without periodontitis at baseline; in practice mostly adults,…

Triclosan/copolymer-containing fluoride toothpaste showed no clear difference in calculus at 7 months (Volpe-Manhold Calculus Index, mean height of… compared with fluoride toothpaste without triclosan; GRADE not reported.

2 findings from 1 review

Triclosan/copolymer-containing fluoride toothpaste vs Fluoride toothpaste without triclosan

Participant-centred outcomes (quality of life; satisfaction with product) · Children and adults (aged 16 years or less = children, over 16 = adults) without periodontitis at baseline; in practice mostly adults,…

The review found no eligible studies for this question.

1 finding from 1 review