Cochrane · systematic review · CD000363

Insecticide‐treated nets for preventing malaria

Pryce, J, Richardson, M, Lengeler, C · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library

Infectious DiseasesAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
16
current version
GRADE rated
16
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 12.5%Low 4 · 25%Moderate 4 · 25%High 6 · 37.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Insecticide‐treated bed nets and curtains compared to no nets for preventing malaria

Population: people of all ages living in malaria transmission settings
8 questions
OutcomeEffectEvidenceStatus / GRADE
Child mortality from all causes
Insecticide‐treated bed nets and curtains vs no nets
Rate ratio 0.83 [0.77, 0.89]5 studies · 200833 participantsHigh
Plasmodium falciparum uncomplicated episodesg
Insecticide‐treated bed nets and curtains vs no nets
Rate ratio 0.55 [0.48, 0.64]5 studies · 35551 participantsHigh
Plasmodium vivax uncomplicated episodes (cumulative incidence)
Insecticide‐treated bed nets and curtains vs no nets
Risk ratio 0.61 [0.48, 0.77]2 studies · 10967 participantsModerate
Downgraded: imprecision, indirectness
Any Plasmodium spp. uncomplicated episodes
Insecticide‐treated bed nets and curtains vs no nets
Rate ratio 0.5 [0.28, 0.9]1 study · 8395 participantsLow
Downgraded: imprecision, indirectness
P falciparum prevalence
Insecticide‐treated bed nets and curtains vs no nets
Risk ratio 0.83 [0.71, 0.98]6 studies · 18809 participantsHigh
P vivax prevalence
Insecticide‐treated bed nets and curtains vs no nets
Risk ratio 1 [0.75, 1.34]2 studies · 10967 participantsLow
Downgraded: imprecision, indirectness
Severe malaria episodes
Insecticide‐treated bed nets and curtains vs no nets
Rate ratio 0.56 [0.38, 0.82]2 studies · 31173 participantsHigh
Anaemia (mean packed cell volume)
Insecticide‐treated bed nets and curtains vs no nets
Mean difference 1.29 [0.42, 2.16]5 studies · 11489 participantsHigh

Insecticide‐treated bed nets and curtains compared to untreated nets for preventing malaria

Population: people of all ages living in malaria transmission settings
8 questions
OutcomeEffectEvidenceStatus / GRADE
Child mortality from all causes
Insecticide‐treated bed nets and curtains vs untreated nets
Rate ratio 0.67 [0.36, 1.23]2 studies · 25389 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Plasmodium falciparum uncomplicated episodes
Insecticide‐treated bed nets and curtains vs untreated nets
Rate ratio 0.58 [0.44, 0.78]5 studies · 2036 participantsHigh
Plasmodium vivax uncomplicated episodes l
Insecticide‐treated bed nets and curtains vs untreated nets
Rate ratio 0.73 [0.51, 1.05]3 studies · 1535 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Any Plasmodium spp. uncomplicated episodes (cumulative incidence)
Insecticide‐treated bed nets and curtains vs untreated nets
Risk ratio 0.47 [0.17, 1.28]2 studies · 8082 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency, indirectness
P falciparum prevalence
Insecticide‐treated bed nets and curtains vs untreated nets
Risk ratio 0.91 [0.78, 1.05]3 studies · 2259 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency, indirectness
P vivax prevalence
Insecticide‐treated bed nets and curtains vs untreated nets
Risk ratio 0.68 [0.25, 1.85]1 study · 350 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Any Plasmodium spp. prevalence
Insecticide‐treated bed nets and curtains vs untreated nets
Risk ratio 0.17 [0.05, 0.53]1 study · 924 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Anaemia (mean packed cell volume)
Insecticide‐treated bed nets and curtains vs untreated nets
Mean difference 0.482 studies · 1909 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness