Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

70 questions · 70 findings · 15 reviews · Headline outcomes only

No studies found 23 · 32.9%GRADE not reported 2 · 2.9%Very low 18 · 25.7%Low 16 · 22.9%Moderate 9 · 12.9%High 2 · 2.9%

Standard care plus IV tranexamic acid vs placebo or usual care

Hysterectomy to control bleeding · women with primary postpartum haemorrhage following vaginal or caesarean birth

Standard care plus IV tranexamic acid showed no clear difference in surgical intervention to control bleeding: Hysterectomy compared with placebo or standard care alone (high certainty).

1 finding from 1 review

Standard care plus IV tranexamic acid vs placebo or usual care

Side effects of the intervention: Any maternal vascular occlusive event · women with primary postpartum haemorrhage following vaginal or caesarean birth

Standard care plus IV tranexamic acid showed no clear difference in side effects of the intervention: Any maternal vascular occlusive… compared with placebo or standard care alone (moderate certainty).

1 finding from 1 review

Inhaled corticosteroids plus standard care vs placebo or usual care

Infections · adults with a confirmed diagnosis of mild COVID‐19, of whom only 10% (219/2132) participants had received ≥ 1 vaccination

Inhaled corticosteroids plus standard care showed no clear difference in infections compared with standard care (with or without placebo) (low certainty).

1 finding from 1 review

Magnetic seizure therapy plus standard care vs electroconvulsive therapy plus standard care

Global state: clinically important change in global state · people with the acute phase of schizophrenia

It is very uncertain whether magnetic seizure therapy plus standard care changes global state: clinically important change assessed by: number of… compared with electroconvulsive therapy plus standard care (very low certainty).

1 finding from 1 review

Magnetic seizure therapy plus standard care vs electroconvulsive therapy plus standard care

Dropout · people with the acute phase of schizophrenia

It is very uncertain whether magnetic seizure therapy plus standard care changes leaving the study early: any reasonassessed by: number of dropouts… compared with electroconvulsive therapy plus standard care (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Corticosteroids plus standard care vs placebo or usual care

All‐cause mortality up to 30 days · hospitalised and unvaccinated individuals with a confirmed or suspected diagnosis of symptomatic COVID‐19

Summary of findings table ‐ Corticosteroids plus standard care probably leads to lower all‐cause mortality up to 30 days compared with standard care (plus/minus placebo) (moderate certainty).

1 finding from 1 review