QoL · people in the prodromal stage of psychosis
1 finding from 1 review
Satisfaction with treatment: leaving the study early Endpoint data (events) · people in the prodromal stage of psychosis
It is very uncertain whether group B cognitive behavioural therapy: cognitive behavioural therapy… changes satisfaction with treatment: leaving the study early Endpoint data… compared with cognitive behavioural therapy + placebo (very low certainty).
1 finding from 1 review
Mental state · schizophrenia
1 finding from 1 review
Global state ‐ number of participants with relapse/exacerbations of psychosis (separated time points) ‐ < 12 months · schizophrenia
It is very uncertain whether summary of findings table ‐ CBT without antipsychotics changes global state ‐ number of participants with relapse/exacerbations of… compared with CBT plus antipsychotics (very low certainty).
1 finding from 1 review
Leaving the study early/ loss to · schizophrenia
It is very uncertain whether summary of findings table ‐ CBT without antipsychotics changes leaving the study early ‐ for any reason ‐ overall acceptability… compared with CBT plus antipsychotics (very low certainty).
1 finding from 1 review
Level of functioning · schizophrenia
1 finding from 1 review
Risk for at least one adverse event per patient · schizophrenia
Summary of findings table ‐ CBT without antipsychotics may leads to lower adverse events ‐ Participants with at least one AE (separated time… compared with CBT plus antipsychotics (low certainty).
1 finding from 1 review
Mental state · recent‐onset psychosis (less than three years since the start of psychotic symptoms and either first or second psychotic episode)
1 finding from 1 review
Global state ‐ number of participants with relapse/exacerbations of psychosis (combined time points) · recent‐onset psychosis (less than three years since the start of psychotic symptoms and either first or second psychotic episode)
Summary of findings table ‐ Cognitive behavioural therapy plus… showed no clear difference in global state ‐ number of participants with relapse/exacerbations of… compared with control (low certainty).
1 finding from 1 review
Leaving the study early ‐ for any reason ‐ overall acceptability (combined time points) · recent‐onset psychosis (less than three years since the start of psychotic symptoms and either first or second psychotic episode)
Summary of findings table ‐ Cognitive behavioural therapy plus… showed no clear difference in leaving the study early ‐ for any reason ‐ overall acceptability… compared with control (moderate certainty).
1 finding from 1 review
Functioning at · recent‐onset psychosis (less than three years since the start of psychotic symptoms and either first or second psychotic episode)
1 finding from 1 review
Risk for at least one adverse event per patient · recent‐onset psychosis (less than three years since the start of psychotic symptoms and either first or second psychotic episode)
It is very uncertain whether summary of findings table ‐ Cognitive behavioural therapy plus… changes adverse events ‐ participants with at least one adverse event ‐ < 12… compared with control (very low certainty).
1 finding from 1 review
Lost to treatment · people with both severe mental illness and substance misuse
Cognitive behavioural therapy + motivational interviewing showed no clear difference in leaving the study early: Lost to treatment compared with standard care (low certainty).
1 finding from 1 review
Adverse event: Death · people with both severe mental illness and substance misuse
Cognitive behavioural therapy + motivational interviewing showed no clear difference in adverse event: Death compared with standard care (low certainty).
1 finding from 1 review
Alcohol use Estimated daily consumption in previous month · people with both severe mental illness and substance misuse
1 finding from 1 review
Drug (non‐alcohol) use Polydrug consumption levels measured by Opiate Treatment Index (OT) · people with both severe mental illness and substance misuse
1 finding from 1 review
Relapse · people with both severe mental illness and substance misuse
It is very uncertain whether cognitive behavioural therapy + motivational interviewing changes relapse:* Relapse at 3 months after 9 months of treatment compared with standard care (very low certainty).
1 finding from 1 review
Global state: average score(GAF scale of 1 ‐ 100) · people with both severe mental illness and substance misuse
1 finding from 1 review
Quality of life / life satisfaction: Brief Quality of Life Scale · people with both severe mental illness and substance misuse
1 finding from 1 review
Lost to treatment · people with both severe mental illness and substance misuse
1 finding from 1 review