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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,463 questions in 125 reviews · Anaesthesia

current versions
No studies 197 · 13.5%Ungraded 203 · 13.9%Very low 307 · 21%Low 441 · 30.1%Moderate 245 · 16.7%High 70 · 4.8%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Paracervical vs systemic analgesia
Postoperative pain · patients with cervical dilatation and uterine intervention
Paracervical local anaesthesia for cervical dilatation and uterine intervention (2013) · Cochrane
no estimate extracted2 studies · 984 participantsHigh
Paracervical vs systemic analgesia
Requirement for postoperative analgesics · patients with cervical dilatation and uterine intervention
Paracervical local anaesthesia for cervical dilatation and uterine intervention (2013) · Cochrane
no estimate extracted1 study · 166 participantsLow
Paracervical vs placebo
Pain during uterine intervention ‐ Risk of any pain · patients with cervical dilatation and uterine intervention
Paracervical local anaesthesia for cervical dilatation and uterine intervention (2013) · Cochrane
RR 0.85 [0.54, 1.34]2 studies · 242 participantsLow
Paracervical vs systemic analgesia
Adverse effects · patients with cervical dilatation and uterine intervention
Paracervical local anaesthesia for cervical dilatation and uterine intervention (2013) · Cochrane
no estimate extracted3 studies · 571 participantsLow
Paracervical vs systemic analgesia
Patient satisfaction · patients with cervical dilatation and uterine intervention
Paracervical local anaesthesia for cervical dilatation and uterine intervention (2013) · Cochrane
no estimate extracted1 study · 166 participantsLow
Paracervical vs placebo
Pain during uterine intervention ‐ Risk of severe pain · patients with cervical dilatation and uterine intervention
Paracervical local anaesthesia for cervical dilatation and uterine intervention (2013) · Cochrane
RR 0.16 [0.04, 0.74]2 studies · 242 participantsModerate
Paracervical vs placebo
Postoperative pain ‐ Immediately after the procedure · patients with cervical dilatation and uterine intervention
Paracervical local anaesthesia for cervical dilatation and uterine intervention (2013) · Cochrane
no estimate extracted3 studies · 223 participantsLow
Paracervical vs placebo
Adverse effects ‐ Nausea and vomiting · patients with cervical dilatation and uterine intervention
Paracervical local anaesthesia for cervical dilatation and uterine intervention (2013) · Cochrane
RR 0.24 [0.02, 2.8]3 studies · 429 participantsModerate
Paracervical vs placebo
Adverse effects ‐ Sweating · patients with cervical dilatation and uterine intervention
Paracervical local anaesthesia for cervical dilatation and uterine intervention (2013) · Cochrane
RR 1.08 [0.7, 1.67]1 study · 142 participantsModerate
Paracervical vs placebo
Adverse effects ‐ Hypotension · patients with cervical dilatation and uterine intervention
Paracervical local anaesthesia for cervical dilatation and uterine intervention (2013) · Cochrane
RR 3.06 [1.21, 7.78]2 studies · 171 participantsModerate
Paracervical vs no anaesthesia
Pain during the procedure · patients with cervical dilatation and uterine intervention
Paracervical local anaesthesia for cervical dilatation and uterine intervention (2013) · Cochrane
OR 0.99 [0.52, 1.86]1 study · 215 participantsHigh
Paracervical vs no anaesthesia
Postoperative pain at different times ‐ Immediately after the procedure · patients with cervical dilatation and uterine intervention
Paracervical local anaesthesia for cervical dilatation and uterine intervention (2013) · Cochrane
no estimate extracted2 studies · 273 participantsHigh
infraclavicular block vs all other brachial plexus blocks
Adequate surgical anaesthesia ‐ At 30 minutes post‐block assessment interval · patients with regional anaesthesia of the lower arm
Infraclavicular brachial plexus block for regional anaesthesia of the lower arm (2013) · Cochrane
RR 0.88 [0.51, 1.52]14 studies · 1051 participantsHigh
infraclavicular block vs all other brachial plexus blocks
Supplementation required to achieve adequate surgical anaesthesia · patients with regional anaesthesia of the lower arm
Infraclavicular brachial plexus block for regional anaesthesia of the lower arm (2013) · Cochrane
RR 0.95 [0.62, 1.46]17 studies · 1412 participantsHigh
infraclavicular block vs all other brachial plexus blocks
Tourniquet pain · patients with regional anaesthesia of the lower arm
Infraclavicular brachial plexus block for regional anaesthesia of the lower arm (2013) · Cochrane
RR 0.66 [0.47, 0.92]8 studies · 615 participantsHigh
infraclavicular block vs all other brachial plexus blocks
Onset time of adequate surgical anaesthesia (minutes) · patients with regional anaesthesia of the lower arm
Infraclavicular brachial plexus block for regional anaesthesia of the lower arm (2013) · Cochrane
no estimate extracted9 studies · 726 participantsModerate
infraclavicular block vs all other brachial plexus blocks
Block performance time (minutes) ‐ multiple‐injection axillary block · patients with regional anaesthesia of the lower arm
Infraclavicular brachial plexus block for regional anaesthesia of the lower arm (2013) · Cochrane
no estimate extracted6 studies · 391 participantsHigh
infraclavicular block vs all other brachial plexus blocks
Block performance time (minutes) ‐ mid‐humeral block · patients with regional anaesthesia of the lower arm
Infraclavicular brachial plexus block for regional anaesthesia of the lower arm (2013) · Cochrane
no estimate extracted2 studies · 224 participantsModerate
Intervention NR
Death (at one month) · participants ventilated by one‐lung
Intravenous versus inhalation anaesthesia for one‐lung ventilation (2013) · Cochrane
RR 0 [0, 0]1 study · 54 participantsVery low
Intervention NR
Adverse postoperative outcomes · participants ventilated by one‐lung
Intravenous versus inhalation anaesthesia for one‐lung ventilation (2013) · Cochrane
1.56 [1.07, 2.29]3 studies · 132 participantsLow
Music interventions vs standard care
Preoperative anxiety (STAI) STAI. Scale from: 20 to 80. · patients with preoperative anxiety
Music interventions for preoperative anxiety (2013) · Cochrane
no estimate extracted13 studies · 896 participantsLow
Music interventions vs standard care
Preoperative anxiety (non‐STAI) VAS, NRS · patients with preoperative anxiety
Music interventions for preoperative anxiety (2013) · Cochrane
no estimate extracted7 studies · 504 participantsLow
Music interventions vs standard care
Heart rate · patients with preoperative anxiety
Music interventions for preoperative anxiety (2013) · Cochrane
no estimate extracted16 studies · 1109 participantsVery low
Music interventions vs standard care
Heart rate variability LF/HF ratio · patients with preoperative anxiety
Music interventions for preoperative anxiety (2013) · Cochrane
no estimate extracted2 studies · 241 participantsVery low
Music interventions vs standard care
Systolic blood pressure · patients with preoperative anxiety
Music interventions for preoperative anxiety (2013) · Cochrane
no estimate extracted14 studies · 809 participantsVery low
Music interventions vs standard care
Diastolic blood pressure · patients with preoperative anxiety
Music interventions for preoperative anxiety (2013) · Cochrane
no estimate extracted13 studies · 786 participantsVery low
Music interventions vs standard care
Respiratory rate · patients with preoperative anxiety
Music interventions for preoperative anxiety (2013) · Cochrane
no estimate extracted6 studies · 375 participantsVery low
Neuraxial vs general anaesthesia
Mortality-At any time · participants with lower‐limb revascularization
Neuraxial anaesthesia for lower‐limb revascularization (2013) · Cochrane
OR 0.89 [0.38, 2.07]4 studies · 696 participantsLow
Neuraxial vs general anaesthesia
Myocardial infarction-Spinal anaesthesia · participants with lower‐limb revascularization
Neuraxial anaesthesia for lower‐limb revascularization (2013) · Cochrane
OR 1.89 [0.5, 7.21]2 studies · 306 participantsLow
Neuraxial vs general anaesthesia
Myocardial infarction-Epidural anaesthesia · participants with lower‐limb revascularization
Neuraxial anaesthesia for lower‐limb revascularization (2013) · Cochrane
OR 0.98 [0.37, 2.58]3 studies · 390 participantsLow
Neuraxial vs general anaesthesia
Amputation rate-Spinal anaesthesia · participants with lower‐limb revascularization
Neuraxial anaesthesia for lower‐limb revascularization (2013) · Cochrane
OR 1.04 [0.35, 3.06]2 studies · 235 participantsLow
Neuraxial vs general anaesthesia
Amputation rate-Epidural anaesthesia · participants with lower‐limb revascularization
Neuraxial anaesthesia for lower‐limb revascularization (2013) · Cochrane
OR 0.66 [0.21, 2.07]2 studies · 230 participantsLow
Neuraxial vs general anaesthesia
Pneumonia · participants with lower‐limb revascularization
Neuraxial anaesthesia for lower‐limb revascularization (2013) · Cochrane
OR 0.37 [0.15, 0.89]2 studies · 201 participantsVery low
Perioperative statins vs placebo or no treatment
All‐cause mortality · participants with improving outcomes during and after noncardiac vascular surgery.
Perioperative statin therapy for improving outcomes during and after noncardiac vascular surgery (2013) · Cochrane
RR 0.73 [0.31, 1.75]3 studies · 178 participantsLow
Perioperative statins vs placebo or no treatment
Death from cardiovascular causes · participants with improving outcomes during and after noncardiac vascular surgery.
Perioperative statin therapy for improving outcomes during and after noncardiac vascular surgery (2013) · Cochrane
RR 1.05 [0.07, 16.2]3 studies · 178 participantsLow
Perioperative statins vs placebo or no treatment
Myocardial infarction (non‐fatal) · participants with improving outcomes during and after noncardiac vascular surgery.
Perioperative statin therapy for improving outcomes during and after noncardiac vascular surgery (2013) · Cochrane
RR 0.47 [0.15, 1.52]3 studies · 178 participantsModerate
Perioperative statins vs placebo or no treatment
Stroke/TIA (non‐fatal) · participants with improving outcomes during and after noncardiac vascular surgery.
Perioperative statin therapy for improving outcomes during and after noncardiac vascular surgery (2013) · Cochrane
RR 0.24 [0.03, 2.25]3 studies · 178 participantsLow
Perioperative statins vs placebo or no treatment
Participant‐reported outcomes-not measured · participants with improving outcomes during and after noncardiac vascular surgery.
Perioperative statin therapy for improving outcomes during and after noncardiac vascular surgery (2013) · Cochrane
no estimate extractedNRNo studies
Perioperative statins vs placebo or no treatment
Adverse muscle effects · participants with improving outcomes during and after noncardiac vascular surgery.
Perioperative statin therapy for improving outcomes during and after noncardiac vascular surgery (2013) · Cochrane
no estimate extracted3 studies · 188 participantsUngraded
PLMA vs tracheal tube
Failed placement/change of device · airway management during general anaesthesia in obese participants
Supraglottic airway devices versus tracheal intubation for airway management during general anaesthesia in… (2013) · Cochrane
no estimate extracted2 studies · 118 participantsLow
PLMA vs tracheal tube
Episodes of hypoxaemia in PACU < 92% oxygen saturation · airway management during general anaesthesia in obese participants
Supraglottic airway devices versus tracheal intubation for airway management during general anaesthesia in… (2013) · Cochrane
RR 0.27 [0.1, 0.72]1 study · 70 participantsModerate
PLMA vs tracheal tube
Oxygen saturation of peripheral blood (%) in PACU · airway management during general anaesthesia in obese participants
Supraglottic airway devices versus tracheal intubation for airway management during general anaesthesia in… (2013) · Cochrane
no estimate extracted2 studies · 204 participantsLow
PLMA vs tracheal tube
Pulmonary aspiration of gastric contents · airway management during general anaesthesia in obese participants
Supraglottic airway devices versus tracheal intubation for airway management during general anaesthesia in… (2013) · Cochrane
no estimate extracted2 studies · 232 participantsUngraded
PLMA vs tracheal tube
Serious respiratory complications and mortality-not reported · airway management during general anaesthesia in obese participants
Supraglottic airway devices versus tracheal intubation for airway management during general anaesthesia in… (2013) · Cochrane
no estimate extractedNRNo studies
PLMA vs tracheal tube
Laryngospasm/bronchoconstriction between induction and recovery · airway management during general anaesthesia in obese participants
Supraglottic airway devices versus tracheal intubation for airway management during general anaesthesia in… (2013) · Cochrane
RR 0.5 [0.09, 2.84]2 studies · 232 participantsVery low
PLMA vs tracheal tube
Time to secure airway · airway management during general anaesthesia in obese participants
Supraglottic airway devices versus tracheal intubation for airway management during general anaesthesia in… (2013) · Cochrane
no estimate extracted1 study · 70 participantsLow
Nurse‐led vs doctor‐led POA
Cancellation for clinical reasons · elective surgical patients requiring regional or general anaesthesia
Nurse‐led versus doctor‐led preoperative assessment for elective surgical patients requiring regional or… (2013) · Cochrane
no estimate extracted0 studies · 0 participantsUngraded
Nurse‐led vs doctor‐led POA
Cancellation by patient · elective surgical patients requiring regional or general anaesthesia
Nurse‐led versus doctor‐led preoperative assessment for elective surgical patients requiring regional or… (2013) · Cochrane
no estimate extracted0 studies · 0 participantsUngraded
Nurse‐led vs doctor‐led POA
Patient satisfaction with POA · elective surgical patients requiring regional or general anaesthesia
Nurse‐led versus doctor‐led preoperative assessment for elective surgical patients requiring regional or… (2013) · Cochrane
no estimate extracted1 study · 42 participantsUngraded
Nurse‐led vs doctor‐led POA
Gain in patient information or knowledge · elective surgical patients requiring regional or general anaesthesia
Nurse‐led versus doctor‐led preoperative assessment for elective surgical patients requiring regional or… (2013) · Cochrane
no estimate extracted0 studies · 0 participantsUngraded