What do systematic reviews say?

Mohs micrographic surgery vs surgical excision

The review found no eligible studies for this question.

• Interventions for basal cell carcinoma of the skin 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

The intervention showed no clear difference in infectious complications (infectious complication after surgery… (low certainty).

• Perioperative glycaemic control for people with diabetes undergoing surgery 2023 · Cochrane Headline outcomes only
  RR 0.75 [0.55, 1.04]
  18 studies · 2453 participants
  Low

Vaginal hysterectomy vs sacral hysteropexy/cervicopexy (uterine prolapse)

Vaginal hysterectomy showed no clear difference in surgery for recurrent prolapse compared with sacral hysteropexy/cervicopexy (uterine prolapse) (low certainty).

• Surgery for women with apical vaginal prolapse 2023 · Cochrane Headline outcomes only
  RR 0.85 [0.47, 1.54]
  5 studies · 403 participants
  Low

Vaginal hysteropexy vs sacral hysteropexy (uterine prolapse)

Vaginal hysteropexy showed no clear difference in surgery for recurrent prolapse compared with sacral hysteropexy (uterine prolapse) (moderate certainty).

• Surgery for women with apical vaginal prolapse 2023 · Cochrane Headline outcomes only
  RR 1.34 [0.52, 3.44]
  2 studies · 345 participants
  Moderate

Vaginal procedure vs sacral colpopexy (vault prolapse)

Vaginal procedure probably leads to higher surgery for recurrent prolapse compared with sacral colpopexy (vault prolapse) (moderate certainty).

• Surgery for women with apical vaginal prolapse 2023 · Cochrane Headline outcomes only
  RR 2.33 [1.34, 4.04]
  6 studies · 497 participants
  Moderate

Vaginal hysterectomy vs vaginal hysteropexy (uterine prolapse)

Vaginal hysterectomy showed no clear difference in surgery for recurrent prolapse compared with vaginal hysteropexy (uterine prolapse) (moderate certainty).

• Surgery for women with apical vaginal prolapse 2023 · Cochrane Headline outcomes only
  RR 1.32 [0.67, 2.6]
  3 studies · 443 participants
  Moderate

Vaginal uterosacral colpopexy vs alternative vaginal native tissue apical suspension

Vaginal uterosacral colpopexy showed no clear difference in surgery for recurrent prolapse compared with alternative vaginal native tissue apical suspension (moderate certainty).

• Surgery for women with apical vaginal prolapse 2023 · Cochrane Headline outcomes only
  RR 1.86 [0.66, 5.28]
  1 study · 228 participants
  Moderate

Absorbable vs non‐absorbable sutures

• Surgery for women with apical vaginal prolapse 2023 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 222 participants
  High

Sacral colpopexy: laparoscopic vs alternative approach

Sacral colpopexy: laparoscopic showed no clear difference in surgery for recurrent prolapse compared with alternative approach (moderate certainty).

• Surgery for women with apical vaginal prolapse 2023 · Cochrane Headline outcomes only
  RR 0.77 [0.26, 2.31]
  3 studies · 208 participants
  Moderate

Tranexamic acid vs placebo (saline solution or sterile water)

• Tranexamic acid for the reduction of bleeding during functional endoscopic sinus surgery 2023 · Cochrane Headline outcomes only
  no estimate extracted
  13 studies · 772 participants
  Moderate

Tranexamic acid vs placebo (saline solution or sterile water)

• Tranexamic acid for the reduction of bleeding during functional endoscopic sinus surgery 2023 · Cochrane Headline outcomes only
  no estimate extracted
  12 studies · 802 participants
  Low

Tranexamic acid vs placebo (saline solution or sterile water)

Tranexamic acid showed no clear difference in significant adverse events (seizures, thromboembolism) within 24… compared with placebo (saline solution or sterile water) (moderate certainty).

• Tranexamic acid for the reduction of bleeding during functional endoscopic sinus surgery 2023 · Cochrane Headline outcomes only
  RD 0
  8 studies · 664 participants
  Moderate

Tranexamic acid vs placebo (saline solution or sterile water)

• Tranexamic acid for the reduction of bleeding during functional endoscopic sinus surgery 2023 · Cochrane Headline outcomes only
  no estimate extracted
  10 studies · 666 participants
  Moderate

Tranexamic acid vs placebo (saline solution or sterile water)

Tranexamic acid showed no clear difference in incomplete surgery compared with placebo (saline solution or sterile water) (moderate certainty).

• Tranexamic acid for the reduction of bleeding during functional endoscopic sinus surgery 2023 · Cochrane Headline outcomes only
  RD 0
  2 studies · 58 participants
  Moderate

Tranexamic acid vs placebo (saline solution or sterile water)

Tranexamic acid showed no clear difference in postoperative bleeding (place of packing or revision surgery within… compared with placebo (saline solution or sterile water) (low certainty).

• Tranexamic acid for the reduction of bleeding during functional endoscopic sinus surgery 2023 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 404 participants
  Low

Intervention not reported

• Effects of interventions targeting the systemic inflammatory response to cardiac surgery on clinical outcomes in adults 2023 · Cochrane Headline outcomes only
  no estimate extracted
  152 studies · 6485 participants
  Very low

Intervention not reported

• Effects of interventions targeting the systemic inflammatory response to cardiac surgery on clinical outcomes in adults 2023 · Cochrane Headline outcomes only
  no estimate extracted
  72 studies · 2963 participants
  Very low

Intervention not reported

The intervention showed no clear difference in knee surgery (replacement or osteotomy)Last (low certainty).

• Arthroscopic surgery for degenerative knee disease (osteoarthritis including degenerative meniscal tears) 2022 · Cochrane Headline outcomes only
  RR 2.63 [0.94, 7.34]
  4 studies · 864 participants
  Low

Phaco‐AIT vs Phaco‐Trab

It is very uncertain whether phaco‐AIT changes proportion of participants who required further glaucoma surgery at… compared with phaco‐Trab (very low certainty).

• Ab interno trabecular bypass surgery with Trabectome for open‐angle glaucoma 2021 · Cochrane Headline outcomes only
  OR 3
  1 study · 18 participants
  Very low

Hydrus microstent vs iStent trabecular micro‐bypass stent

• Ab interno trabecular bypass surgery with Schlemm´s canal microstent (Hydrus) for open angle glaucoma 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 148 participants
  Very low