Cochrane · systematic review · CD007315

Perioperative glycaemic control for people with diabetes undergoing surgery

Bellon, F, Solà, I, Gimenez-Perez, G, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library

Metabolic and Endocrine Disorders2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 14.3%Low 5 · 71.4%Moderate 0 · 0%High 1 · 14.3%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Show all 2 versions

Summary of findings: perioperative control for people with diabetes undergoing surgery

7 questions
OutcomeEffectEvidenceStatus / GRADE
All‐cause mortality (death from any cause)
RR 1.08 [0.88, 1.33]18 studies · 2551 participantsHigh
Severe hypoglycaemic episodes (number of severe hypoglycaemic episodes)
RR 4.73 [2.12, 10.55]11 studies · 1896 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Infectious complications (infectious complication after surgery (e.g. pneumonia, urinary tract infection))
RR 0.75 [0.55, 1.04]18 studies · 2453 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Cardiovascular events (incidents that may cause damage to the cardiovascular system)
RR 0.73 [0.55, 0.97]12 studies · 1454 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Renal failure (number of individuals with an elevation of serum creatinine greater than 2 mg/dL or requiring dialysis)
RR 0.92 [0.69, 1.22]14 studies · 2086 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Length of ICU stay (days admitted to the ICU unit)
no estimate extracted11 studies · 1687 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Length of hospital stay (days admitted to the hospital)
no estimate extracted12 studies · 1520 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness