Cochrane · systematic review · CD007315
Perioperative glycaemic control for people with diabetes undergoing surgery
Bellon, F, Solà, I, Gimenez-Perez, G, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 14.3%Low 5 · 71.4%Moderate 0 · 0%High 1 · 14.3%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlySummary of findings: perioperative control for people with diabetes undergoing surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All‐cause mortality (death from any cause) | RR 1.08 [0.88, 1.33] | 18 studies · 2551 participants | High |
Severe hypoglycaemic episodes (number of severe hypoglycaemic episodes) | RR 4.73 [2.12, 10.55] | 11 studies · 1896 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Infectious complications (infectious complication after surgery (e.g. pneumonia, urinary tract infection)) | RR 0.75 [0.55, 1.04] | 18 studies · 2453 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Cardiovascular events (incidents that may cause damage to the cardiovascular system) | RR 0.73 [0.55, 0.97] | 12 studies · 1454 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Renal failure (number of individuals with an elevation of serum creatinine greater than 2 mg/dL or requiring dialysis) | RR 0.92 [0.69, 1.22] | 14 studies · 2086 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Length of ICU stay (days admitted to the ICU unit) | no estimate extracted | 11 studies · 1687 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Length of hospital stay (days admitted to the hospital) | no estimate extracted | 12 studies · 1520 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Comparison
Population: Diabetic patients undergoing surgery
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death from any cause (20 to 90 days | RR 1.19 [0.89, 1.59] | 11 studies · 1365 participants | High |
Infectious complications (48 h to 90 days | RR 0.46 [0.18, 1.18] | 8 studies · 627 participants | Moderate Downgraded: imprecision |
Cardiovascular events (4 to 30 days | RR 1.03 [0.21, 5.13] | 6 studies · 682 participants | Moderate Downgraded: imprecision |
Renal failure (48 h to 90 days | RR 0.61 [0.34, 1.08] | 2 studies · 434 participants | Moderate Downgraded: imprecision |
Hypoglycaemic episodes (18 h to 90 days | RR 6.92 [2.04, 23.41] | 3 studies · 724 participants | Low Downgraded: imprecision |
Health‐related quality of life SF‐12 physical component score (6 months | no estimate extracted | 1 study · 25 participants | Low Downgraded: imprecision |
Length of intensive care unit (ICU) or hospital stay ( | no estimate extracted | 9 studies · 1060 participants | Moderate Downgraded: imprecision |