Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

929 questions · 946 findings · 295 reviews · Headline outcomes only

No studies found 150 · 15.9%GRADE not reported 47 · 5%Very low 312 · 33%Low 262 · 27.7%Moderate 138 · 14.6%High 37 · 3.9%

Intervention not reported

Proportion of participants who lost two or more lines of best‐corrected visual acuity (BCVA) · participants aged 18‐60 years with myopia ranging in severity up to 12 diopters (D)

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Number of attempts at intubation and unsuccessful intubations assessed as unsuccessful or required more than 2 attempts at intubation · tracheal intubation in children (excluding neonates)

The intervention may leads to higher number of attempts at intubation and unsuccessful intubations… (low certainty).

1 finding from 1 review

Intervention not reported

Depression: Geriatric Depression Scale (GDS15) A 15‐item self‐report assessment used to identify depression in the elderly. A yes/no response is required for each item (score 0 or 1). Cummulative score: 0‐4 normal, 5‐9 Mild depression, 10‐15 More ... · adults with stroke
1 finding from 1 review

Cuffed vs uncuffed tubes

Need for ETT exchange (defined as more than one attempt to arrive at the final endotracheal tube size) · Children up to eight years undergoing general anaesthesia

It is very uncertain whether cuffed changes need for ETT exchange (defined as more than one attempt to arrive at… compared with uncuffed tubes (very low certainty).

1 finding from 1 review

Direct‐acting antivirals vs control

Proportion of participants with one or more serious adverse event at maximum · adults with chronic hepatitis C

It is very uncertain whether direct‐acting antivirals changes proportion of participants with one or more serious adverse event at… compared with control (very low certainty).

1 finding from 1 review

Direct‐acting antivirals withdrawn from the market vs control

Proportion of participants with one or more serious adverse event at maximum · adults with chronic hepatitis C

It is very uncertain whether direct‐acting antivirals withdrawn from the market changes proportion of participants with one or more serious adverse event at… compared with control (very low certainty).

1 finding from 1 review

Adherence education vs controls

Unsheduled visits to a healthcare provider (people with 1 or more) WMD of · people with asthma

It is very uncertain whether adherence education changes unsheduled visits to a healthcare provider (people with 1 or more)… compared with controls (very low certainty).

1 finding from 1 review

Intervention not reported

Motor development and vigor (MDV) domain of the NAPI tool Normative mean and SD at 36 weeks PMA 63 (14.5) Higher scores are associated with more mature behaviour (Snider 2005) · neonates with pain associated with potentially painful procedures for 7 days
1 finding from 1 review

Intervention not reported

Alertness and orientation (AO) domain of the NAPI tool Normative mean and SD at 36 weeks PMA 54 (19.4) Higher scores are associated with more mature behaviour (Snider 2005) · neonates with pain associated with potentially painful procedures for 7 days
1 finding from 1 review

Surgery vs LNG‐IUS

Subjective control of bleeding: PBAC no more than 75 per cycle Endometrial resection or ablation versus LNG‐IUS At 1 year · women with heavy menstrual bleeding

Surgery may leads to higher subjective control of bleeding: PBAC no more than 75 per cycle… compared with LNG‐IUS (low certainty).

1 finding from 1 review