Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

2,289 questions · 2,331 findings · 195 reviews · Pregnancy and Childbirth

No studies found 480 · 20.6%GRADE not reported 288 · 12.4%Very low 467 · 20%Low 630 · 27%Moderate 338 · 14.5%High 128 · 5.5%

Remifentanil (PCA) vs epidural/CSE

Maternal respiratory depression (< 9, < 8 breaths/min) · women in labour with planned vaginal delivery

Remifentanil (PCA) showed no clear difference in maternal respiratory depression (< 9, < 8 breaths/min) compared with epidural/CSE (low certainty).

1 finding from 1 review

Remifentanil (PCA) vs remifentanil (continuous IV)

Maternal respiratory depression (< 8 breaths/min) · women in labour with planned vaginal delivery

Remifentanil (PCA) may leads to lower maternal respiratory depression (< 8 breaths/min) compared with remifentanil (continuous IV) (low certainty).

1 finding from 1 review

Magnesium sulphate vs placebo (outcomes

Death (fetal, neonatal, or later (up to 2 years' corrected age))** · women at risk of preterm birth (< 34 weeks' gestation)

Magnesium sulphate showed no clear difference in death (fetal, neonatal, or later (up to 2 years' corrected age))** compared with placebo (outcomes (moderate certainty).

1 finding from 1 review

Magnesium sulphate vs placebo (outcomes

Death or cerebral palsy · women at risk of preterm birth (< 34 weeks' gestation)

Magnesium sulphate showed no clear difference in death or cerebral palsy (up to school age)** compared with placebo (outcomes (low certainty).

2 findings from 1 review

Magnesium sulphate vs placebo (outcomes

Major neurodevelopmental disability at childhood · women at risk of preterm birth (< 34 weeks' gestation)

It is very uncertain whether magnesium sulphate changes major neurodevelopmental disability (school age)** compared with placebo (outcomes (very low certainty).

1 finding from 1 review