Question · asked by 1 review
Remifentanil (PCA) vs epidural/CSE: Maternal respiratory depression (< 9, < 8 breaths/min)
- Population
- women in labour with planned vaginal delivery
- Intervention
- Remifentanil (PCA)
- Comparison
- epidural/CSE
- Outcome
- Maternal respiratory depression (< 9, < 8 breaths/min)
Remifentanil (PCA) showed no clear difference in maternal respiratory depression (< 9, < 8 breaths/min) compared with epidural/CSE (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Remifentanil (PCA) vs epidural/CSE Maternal respiratory depression (< 9, < 8 breaths/min) · women in labour with planned vaginal delivery Remifentanil (PCA) showed no clear difference in maternal respiratory depression (< 9, < 8 breaths/min) compared with epidural/CSE (low certainty). Patient‐controlled analgesia with remifentanil versus alternative parenteral methods for pain management in… (2017) · Cochrane Headline outcomes only | RR 0.91 [0.51, 1.62] | 3 studies · 687 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Patient‐controlled analgesia with remifentanil versus alternative parenteral methods for pain management in labour 2017 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.