Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,938 questions · 1,994 findings · 246 reviews · Headline outcomes only

No studies found 490 · 24.6%GRADE not reported 71 · 3.6%Very low 669 · 33.6%Low 446 · 22.4%Moderate 264 · 13.2%High 54 · 2.7%

Infraclavicular block vs all other brachial plexus blocks

Adequate surgical anaesthesia ‐ At 30 minutes post‐block assessment interval · patients with regional anaesthesia of the lower arm

infraclavicular block showed no clear difference in adequate surgical anaesthesia ‐ At 30 minutes post‐block assessment… compared with all other brachial plexus blocks (high certainty).

1 finding from 1 review

Infraclavicular block vs all other brachial plexus blocks

Supplementation required for surgical anaesthesia · patients with regional anaesthesia of the lower arm

infraclavicular block showed no clear difference in supplementation required to achieve adequate surgical anaesthesia compared with all other brachial plexus blocks (high certainty).

1 finding from 1 review

Intervention not reported

Surgical failure (intraocular pressure >21mmHg) ( · patients with glaucoma surgery

The intervention probably leads to lower surgical failure (intraocular pressure >21mmHg) ( (moderate certainty).

1 finding from 1 review

Transcatheter aortic valve implantation vs surgical aortic valve replacement

All‐cause mortality · adults with severe aortic stenosis who are at a low surgical risk.

Transcatheter aortic valve implantation showed no clear difference in all‐cause mortality compared with surgical aortic valve replacement (moderate certainty).

1 finding from 1 review

Transcatheter aortic valve implantation vs surgical aortic valve replacement

Stroke · adults with severe aortic stenosis who are at a low surgical risk.

Transcatheter aortic valve implantation showed no clear difference in stroke compared with surgical aortic valve replacement (moderate certainty).

1 finding from 1 review

Transcatheter aortic valve implantation vs surgical aortic valve replacement

Patient readmissions · adults with severe aortic stenosis who are at a low surgical risk.

Transcatheter aortic valve implantation showed no clear difference in rehospitalisation compared with surgical aortic valve replacement (low certainty).

1 finding from 1 review

Transcatheter aortic valve implantation vs surgical aortic valve replacement

Myocardial infarction · adults with severe aortic stenosis who are at a low surgical risk.

Transcatheter aortic valve implantation showed no clear difference in myocardial infarction compared with surgical aortic valve replacement (moderate certainty).

1 finding from 1 review

Transcatheter aortic valve implantation vs surgical aortic valve replacement

Cardiac mortality · adults with severe aortic stenosis who are at a low surgical risk.

Transcatheter aortic valve implantation showed no clear difference in cardiac death compared with surgical aortic valve replacement (moderate certainty).

1 finding from 1 review

Transcatheter aortic valve implantation vs surgical aortic valve replacement

Permanent pacemaker implantation · adults with severe aortic stenosis who are at a low surgical risk.

Transcatheter aortic valve implantation probably leads to higher permanent pacemaker implantation compared with surgical aortic valve replacement (moderate certainty).

1 finding from 1 review