Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,192 questions · 1,243 findings · 151 reviews

No studies found 252 · 20.3%GRADE not reported 180 · 14.5%Very low 291 · 23.4%Low 282 · 22.7%Moderate 174 · 14%High 64 · 5.1%

Intervention not reported

Total hip arthroplasty (single articulation) (3 RCTs; 306 participants)a · older adults (> 60 years of age) with intracapsular hip fractures; most fractures in the included studies were displaced

It is very uncertain whether the intervention changes total hip arthroplasty (single articulation) (3 RCTs; 306… (very low certainty).

1 finding from 1 review

Intervention not reported

Total hip arthroplasty (single articulation) (2 RCTs; 225 participants)a · older adults (> 60 years of age) with intracapsular hip fractures; most fractures in the included studies were displaced

It is very uncertain whether the intervention changes total hip arthroplasty (single articulation) (2 RCTs; 225… (very low certainty).

1 finding from 1 review

Albendazole vs placebo or no anthelmintics

Seizure recurrence ‐ participants with a single cyst · people with neurocysticercosis

Albendazole probably leads to lower seizure recurrence ‐ participants with a single cyst compared with placebo or no anthelmintics (moderate certainty).

1 finding from 1 review

Interventions delivered by dental professionals vs control

Smoking cessation · participants who used tobacco products

It is very uncertain whether interventions delivered by dental professionals changes single session behavioural support versus usual care, brief advice,… compared with control (very low certainty).

1 finding from 1 review

Wheat flour fortified with iron in combination with other micronutrients vs unfortified wheat flour (no micronutrients added)

Diarrhoea (three liquid stools in a single day) (only in children 2 to 11 years of age) · general population of all age groups (including pregnant women) from any country, over two years of age
1 finding from 1 review

iron‐fortified wheat flour with or without other micronutrients added vs fortified wheat flour with same micronutrients (but not iron)

Diarrhoea (three liquid stools in a single day) (only in children 2 to 11 years of age) · general population of all age groups (including pregnant women) from any country, over two years of age
1 finding from 1 review

All fluorescence-based devices (red, blue, and green fluorescence combined) vs Reference standard (histology, excavation, or enhanced visual examination)

Diagnostic odds ratio (DOR) by subgroup: Single site per tooth (detection of early enamel caries, D1 threshold) · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…
1 finding from 1 review

Intervention not reported

Cost of analgesic regimens for single‐injection blocks · patients with hip fracture
1 finding from 1 review

Intervention not reported

Failure to close a patent ductus arteriosus (PDA) (after single or 3 doses) · preterm infants with patent ductus arteriosus

The intervention showed no clear difference in failure to close a patent ductus arteriosus (PDA) (after single or 3… (moderate certainty).

1 finding from 1 review

Intervention not reported

Bayley‐II MDI at 18 to 24 months Bayley Scales of Infant Development, Second Edition, yields 2 single age‐standardised composite scores (range 50 to 150): a Mental Development Index (MDI), which measures cognition through sensory perception, knowl... · preterm infants with low birth weight
1 finding from 1 review

Intervention not reported

Multifocal vs single vision lens spectacles · children with myopia (nearsightedness)
1 finding from 1 review

Intervention not reported

Peripheral plus spectacles vs single vision lens spectacles · children with myopia (nearsightedness)
1 finding from 1 review

Intervention not reported

Bifocal vs single vision soft contact lenses · children with myopia (nearsightedness)
1 finding from 1 review

Intervention not reported

Orthokeratology contact lenses vs single vision lenses · children with myopia (nearsightedness)

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Spherical aberration soft contact lenses vs single vision soft contact lenses · children with myopia (nearsightedness)
1 finding from 1 review

Equivalent schedules of intradermal fractional‐dose inactivated poliovirus vaccine vs intramuscular inactivated poliovirus vaccine

Seroconversion rate (after a single primary dose) · children

Equivalent schedules of intradermal fractional‐dose inactivated… may leads to lower seroconversion rate (after a single primary dose) compared with intramuscular inactivated poliovirus vaccine (low certainty).

1 finding from 1 review