Cochrane · systematic review · CD000215

Anthelmintics for people with neurocysticercosis

Monk, EJM, Abba, K, Ranganathan, LN · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

Infectious DiseasesAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 20%Low 1 · 20%Moderate 3 · 60%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Albendazole compared with placebo or no anthelmintics for people with neurocysticercosis

Population: people with neurocysticercosis
5 questions
OutcomeEffectEvidenceStatus / GRADE
Seizure recurrence ‐ all participants
Albendazole vs placebo or no anthelmintics
RR 0.94 [0.78, 1.14]10 studies · 1054 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias
Seizure recurrence ‐ participants with a single cyst
Albendazole vs placebo or no anthelmintics
RR 0.61 [0.4, 0.91]5 studies · 396 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias
Seizure recurrence ‐ participants with multiple (> 1) cysts
Albendazole vs placebo or no anthelmintics
RR 2.05 [1.28, 3.31]2 studies · 321 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias
Complete radiological clearance of lesions
Albendazole vs placebo or no anthelmintics
RR 1.22 [1.07, 1.39]13 studies · 1324 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias
Evolution of cysts
Albendazole vs placebo or no anthelmintics
RR 1.27 [1.1, 1.47]6 studies · 434 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias