Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,970 questions · 2,433 findings · 231 reviews

No studies found 303 · 12.5%GRADE not reported 759 · 31.2%Very low 357 · 14.7%Low 476 · 19.6%Moderate 418 · 17.2%High 120 · 4.9%

Summary of findings: Trihexyphenidyl vs placebo

Participation in activities of daily living:individual goal setting Measured by: GAS (up to 5 functional goals scored on a 5‐point scale (−2 = much less than expected to +2 = much more than expected); higher score = better than expected outcome) · children with dystonic cerebral palsy
1 finding from 1 review

Summary of findings: Trihexyphenidyl vs placebo

Participation in activities of daily living:satisfaction with individual goals Measured by: satisfaction subscale of the COPM (satisfaction with performance in up to 5 problem areas scored on a 10‐point scale (1 = not satisfied at all to 10 = extr... · children with dystonic cerebral palsy
1 finding from 1 review

Summary of findings: Trihexyphenidyl vs placebo

Participation in activities of daily living:performance of individual goals Measured by: performance subscale of the COPM (up to five problem areas scored on a 10‐point scale (1 = not able to do to 10 = able to do extremely well; higher score = be... · children with dystonic cerebral palsy
1 finding from 1 review

Zinc vs placebo

Taste acuity improvement - objective outcome (continuous) - individual taste sensations · Patients with taste disturbances (dysgeusia/hypogeusia; idiopathic, zinc-deficient, or secondary to chronic renal failure)

Zinc supplements (zinc sulphate, zinc gluconate, zinc picolinate,… showed no clear difference in taste acuity improvement - objective outcome (continuous) -… compared with placebo; GRADE not reported.

1 finding from 1 review
  • Interventions for managing taste disturbances 2017 · Cochrane All outcomes
    Chronic renal failure
    Results (Mahajan 1980, chronic renal failure; Analysis 1.3): mean difference by taste sensation - salt MD 285 (95% CI 238.75 to 331.25); sweet MD 190 (142.36 to 237.64); sour MD 10 (-16.43 to 36.43); bitter MD 2.40…
    1 study · 22 participants
    GRADE not reported

Group‐format behavioural programmes vs alternative support

Group programme compared to face‐to‐face individual intervention · people who smoke

Group‐format behavioural programmes showed no clear difference in group programme compared to face‐to‐face individual intervention compared with alternative support (moderate certainty).

1 finding from 1 review

Intervention not reported

Residual pleural fluid on chest X‐ray at 8 weeks · adults and adolescents with pleural TB

The intervention may leads to lower residual pleural fluid on chest X‐ray at 8 weeks (low certainty).

1 finding from 1 review

Intervention not reported

Residual pleural fluid on chest X‐ray at 24 weeks · adults and adolescents with pleural TB

The intervention may leads to lower residual pleural fluid on chest X‐ray at 24 weeks (low certainty).

1 finding from 1 review

Intervention not reported

Global state: No clinically important overall improvement (as rated by individual trials) ‐ medium term ( · People with schizophrenia and schizophrenia‐like disorders

The intervention may leads to lower global state: No clinically important overall improvement (as rated… (low certainty).

1 finding from 1 review