Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

62 questions · 73 findings · 26 reviews · Anaesthesia

No studies found 5 · 6.8%GRADE not reported 4 · 5.5%Very low 21 · 28.8%Low 28 · 38.4%Moderate 12 · 16.4%High 3 · 4.1%

Aromatherapy vs placebo

Adverse events (common reactions to aromatherapy include skin rashes, dyspnoea, headache, cardiac arrhythmias, hypotension, hypertension or dizziness) · adults and children having any type of surgical procedure under general anaesthesia, regional anaesthesia or sedation, as hospital…

The review found no eligible studies for this question.

1 finding from 1 review

Peppermint vs placebo

Adverse events (common reactions to aromatherapy include skin rashes, dyspnoea, headache, cardiac arrhythmias, hypotension, hypertension or dizziness) · adults and children having any type of surgical procedure under general anaesthesia, regional anaesthesia or sedation, as hospital…

The review found no eligible studies for this question.

1 finding from 1 review

Perioperative alcohol cessation intervention vs treatment

Postoperative complications after perioperative intervention (e.g. wound‐related complications, secondary surgery, cardiopulmonary complications, admission to intensive care) defined by need for treatment · adult surgical patients consuming 3 or more units of alcohol per day

Perioperative alcohol cessation intervention probably leads to lower postoperative complications after perioperative intervention (e.g.… compared with treatment (moderate certainty).

1 finding from 1 review

Primary outcome: topical local anaesthetics vs infiltrated local anaesthetics or other topical agents

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · adults and paediatric patients with dermal laceration
5 findings from 1 review
Show 2 more findings

Inhalational anaesthesia vs intravenous anaesthesia

Nausea · adults undergoing transabdominal robotic assisted laparoscopic surgery
2 findings from 1 review

Intravenous dexamethasone vs placebo

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · participants undergoing surgery with peripheral nerve block
3 findings from 1 review

Perineural vs intravenous dexamethasone

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · peripheral nerve block
3 findings from 1 review

Perineural dexamethasone vs placebo

Postoperative pain intensity in the immediate postobturation period (up to 72 hours), continuous (VAS) · participants undergoing surgery with peripheral nerve block
3 findings from 1 review

Cuffed vs uncuffed tubes

Need for intensive care unit (ICU) admission to treat post extubation stridor (as defined by the trial authors) · Children up to eight years undergoing general anaesthesia

It is very uncertain whether cuffed changes need for intensive care unit (ICU) admission to treat post… compared with uncuffed tubes (very low certainty).

1 finding from 1 review

Intervention not reported

Mean maternal arterial oxygen tension (mm Hg) (PaO2) · low‐risk term pregnant women undergoing elective caesarean section under regional anaesthesia
1 finding from 1 review

Intervention not reported

Mean oxygen tension (mm Hg) in umbilical artery (UaPO2) · low‐risk term pregnant women undergoing elective caesarean section under regional anaesthesia
1 finding from 1 review

Intervention not reported

Mean oxygen tension (mm Hg) in umbilical vein (UvPO2) · low‐risk term pregnant women undergoing elective caesarean section under regional anaesthesia
1 finding from 1 review

Intervention not reported

High‐intensity pain with lidocaine admixture Pain scales · Adult participants receiving propofol for induction of anaesthesia

The intervention leads to lower high‐intensity pain with lidocaine admixture Pain scales (high certainty).

1 finding from 1 review