Inhaled corticosteroids plus standard care showed no clear difference in symptom resolution: duration to symptoms resolved compared with standard care (with or without placebo) (low certainty).
It is very uncertain whether inhaled corticosteroids plus standard care changes serious adverse events compared with standard care (with or without placebo) (very low certainty).
Inhaled corticosteroids plus standard care showed no clear difference in adverse events compared with standard care (with or without placebo) (low certainty).
Inhaled corticosteroids plus standard care showed no clear difference in infections compared with standard care (with or without placebo) (low certainty).
Effects of different inhaled corticosteroids on growth in children… may leads to higher linear growth velocity (cm/year) compared with beclomethasone (low certainty).
It is very uncertain whether effects of different inhaled corticosteroids on growth in children… changes linear growth velocity (cm/year) compared with budesonide (very low certainty).
Effects of different inhaled corticosteroids on growth in children… probably leads to higher change in height (cm) over a period of time compared with budesonide (moderate certainty).
A boost of inhaled corticosteroids showed no clear difference in exacerbations compared with usual care (moderate certainty).
A boost of inhaled corticosteroids showed no clear difference in adverse events compared with usual care (moderate certainty).
The review found no eligible studies for this question.
Increased showed no clear difference in treatment failure: need for systemic corticosteroids (ITT) compared with stable doses of inhaled corticosteroids (moderate certainty).
It is very uncertain whether increased changes treatment failure: need for systemic corticosteroids (of those… compared with stable doses of inhaled corticosteroids (very low certainty).
The review found no eligible studies for this question.
Increased showed no clear difference in unscheduled physician visits 44 weeks compared with stable doses of inhaled corticosteroids (low certainty).
It is very uncertain whether increased changes serious adverse events 48 weeks compared with stable doses of inhaled corticosteroids (very low certainty).
It is very uncertain whether increased changes non‐serious adverse events 43 weeks compared with stable doses of inhaled corticosteroids (very low certainty).
It is very uncertain whether once‐daily ICS/LABA combined inhalers changes any COPD exacerbation that requires short‐burst oral corticosteroids… compared with once‐daily LAMA (very low certainty).