Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

60 questions · 69 findings · 11 reviews · Dental caries

No studies found 14 · 20.3%GRADE not reported 25 · 36.2%Very low 30 · 43.5%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ceramic inlays (all types) vs Amalgam

Outcome not reported · Adults who require restorative treatment in posterior teeth

The review found no eligible studies for this question.

1 finding from 1 review
  • Ceramic inlays for restoring posterior teeth 2003 · Cochrane All outcomes
    No eligible randomised controlled trial comparing ceramic inlays with amalgam restorations was identified; this planned comparison could not be evaluated.
    0 studies
    No studies found

Ceramic inlays (all types) vs Gold inlay

Aesthetic satisfaction (colour match) · Adults who require restorative treatment in posterior teeth

The review found no eligible studies for this question.

1 finding from 1 review
  • Ceramic inlays for restoring posterior teeth 2003 · Cochrane All outcomes
    Information on aesthetic satisfaction could not be obtained from this study as it did not use the tooth-coloured restorations as the control group.
    0 studies
    No studies found

Ceramic inlays (all types) vs Gold inlay

Postoperative sensitivity · Adults who require restorative treatment in posterior teeth
1 finding from 1 review
  • Ceramic inlays for restoring posterior teeth 2003 · Cochrane All outcomes
    1 week
    Postoperative sensitivity was evaluated 1 week after placement. No teeth with ceramic inlays were found to have postoperative sensitivity, while one tooth with gold inlay presented sensitivity, which lasted more than 2…
    1 study · 20 participants
    GRADE not reported

Ceramic inlays (all types) vs Gold inlay

Failure rate (longevity) at 5 years · Adults who require restorative treatment in posterior teeth

Ceramic inlays (all types) showed no clear difference in failure rate (longevity) at 5 years compared with gold inlay; GRADE not reported.

1 finding from 1 review

Ceramic inlays (all types) vs Composite resin (direct restoration)

Outcome not reported · Adults who require restorative treatment in posterior teeth

The review found no eligible studies for this question.

1 finding from 1 review
  • Ceramic inlays for restoring posterior teeth 2003 · Cochrane All outcomes
    No eligible randomised controlled trial comparing ceramic inlays with composite resin (direct) restorations was identified; this planned comparison could not be evaluated.
    0 studies
    No studies found

Single full-coverage metal-ceramic crown over composite core and post vs Direct adhesive composite restoration with post (conventional filling, no crown)

Cost of the intervention · People with a permanent tooth that has undergone endodontic (root canal) treatment

The review found no eligible studies for this question.

1 finding from 1 review

Single full-coverage metal-ceramic crown over composite core and post vs Direct adhesive composite restoration with post (conventional filling, no crown)

Patient satisfaction / quality of life (validated measure) · People with a permanent tooth that has undergone endodontic (root canal) treatment

The review found no eligible studies for this question.

1 finding from 1 review

Single full-coverage metal-ceramic crown over composite core and post vs Direct adhesive composite restoration with post (conventional filling, no crown)

Catastrophic failure of the restored tooth or restoration leading directly to extraction · People with a permanent tooth that has undergone endodontic (root canal) treatment
1 finding from 1 review

Single full-coverage metal-ceramic crown over composite core and post vs Direct adhesive composite restoration with post (conventional filling, no crown)

Periodontal health status · People with a permanent tooth that has undergone endodontic (root canal) treatment

The review found no eligible studies for this question.

1 finding from 1 review

Single full-coverage metal-ceramic crown over composite core and post vs Direct adhesive composite restoration with post (conventional filling, no crown)

Non-catastrophic failure of the post · People with a permanent tooth that has undergone endodontic (root canal) treatment

It is very uncertain whether single full-coverage metal-ceramic crown over composite core and post changes non-catastrophic failure of the post compared with direct adhesive composite restoration with post (conventional… (very low certainty).

1 finding from 1 review

Single full-coverage metal-ceramic crown over composite core and post vs Direct adhesive composite restoration with post (conventional filling, no crown)

Incidence or recurrence of caries (assessed clinically or by radiographs) · People with a permanent tooth that has undergone endodontic (root canal) treatment

The review found no eligible studies for this question.

1 finding from 1 review

Single full-coverage metal-ceramic crown over composite core and post vs Direct adhesive composite restoration with post (conventional filling, no crown)

Non-catastrophic failure of the restoration (requiring further treatment) · People with a permanent tooth that has undergone endodontic (root canal) treatment

It is very uncertain whether single full-coverage metal-ceramic crown over composite core and post changes non-catastrophic failure of the restoration (requiring further… compared with direct adhesive composite restoration with post (conventional… (very low certainty).

1 finding from 1 review

Inflammatory bowel disease (IBD) vs Healthy controls without IBD

Periodontal disease (periodontitis) coincidence · Patients with inflammatory bowel disease (IBD) and controls without IBD; mostly adults (one pediatric study), both sexes

Patients with IBD have about 2.5-fold higher odds of coexisting periodontal disease than healthy controls (pooled OR 2.49, 95% CI 1.97-3.15; 6 studies; not GRADE-rated).

1 finding from 1 review

Metal-free implant-supported FDPs (zirconia-toughened alumina; In-Ceram Zirconia) vs Metal-free implant-supported FDPs (yttria-stabilized tetragonal zirconia; Denzir)

Periodontal/peri-implant status (secondary outcomes) · Adults (18 years or older) needing an implant-supported fixed dental prosthesis in the posterior region

The review found no eligible studies for this question.

1 finding from 1 review

Metal-free implant-supported FDPs (zirconia-toughened alumina; In-Ceram Zirconia) vs Metal-free implant-supported FDPs (yttria-stabilized tetragonal zirconia; Denzir)

Bridge complications · Adults (18 years or older) needing an implant-supported fixed dental prosthesis in the posterior region

It is very uncertain whether metal-free implant-supported FDPs (zirconia-toughened alumina;… changes bridge complications compared with metal-free implant-supported FDPs (yttria-stabilized tetragonal… (very low certainty).

4 findings from 1 review
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Metal-free implant-supported FDPs (zirconia-toughened alumina; In-Ceram Zirconia) vs Metal-free implant-supported FDPs (yttria-stabilized tetragonal zirconia; Denzir)

Bridge failure · Adults (18 years or older) needing an implant-supported fixed dental prosthesis in the posterior region
1 finding from 1 review

Metal-free implant-supported FDPs (zirconia-toughened alumina; In-Ceram Zirconia) vs Metal-free implant-supported FDPs (yttria-stabilized tetragonal zirconia; Denzir)

Aesthetics · Adults (18 years or older) needing an implant-supported fixed dental prosthesis in the posterior region

The review found no eligible studies for this question.

1 finding from 1 review

Living with HIV and undergoing antiretroviral therapy (ART/HAART) vs Healthy HIV-negative controls

Ulcerative stomatitis · Children or adolescents

One study found significantly higher ulcerative stomatitis among CLWH on ART (OR 28.59, 95% CI 1.67 to 490.32), though the estimate is very imprecise.

1 finding from 1 review

Antiretroviral therapy (any, including cART) vs No antiretroviral medication (treatment-naive)

Acute necrotising ulcerative gingivitis prevalence · Children and adolescents (<18 years) living with HIV (CLWH)

Acute necrotising ulcerative gingivitis was significantly more prevalent in treatment-naive CLWH than in those on ART (very low certainty).

1 finding from 1 review