Inflammatory bowel disease (IBD) vs Healthy controls without IBD: Periodontal disease (periodontitis) coincidence
Patients with IBD have about 2.5-fold higher odds of coexisting periodontal disease than healthy controls (pooled OR 2.49, 95% CI 1.97-3.15; 6 studies; not GRADE-rated).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Inflammatory bowel disease (IBD; Crohn's disease or ulcerative colitis) vs Healthy controls without IBD Periodontal disease (periodontitis) coincidence · Patients with inflammatory bowel disease (IBD) and controls without IBD; mostly adults (one pediatric study), both sexes · Hospital/clinic-based case-control and cross-sectional studies in 11 countries; 15 studies total (1748 participants: 1104 Crohn's disease, 534 ulcerative colitis, 110 IBD-form unspecified); 6 studies pooled for this analysis Patients with IBD have about 2.5-fold higher odds of coexisting periodontal disease than healthy controls (pooled OR 2.49, 95% CI 1.97-3.15; 6 studies; not GRADE-rated). Oral Health Status in Patients with Inflammatory Bowel Diseases: A Systematic Review. (2021) All outcomes | OR 2.49 [1.97, 3.15] | 6 studies | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Oral Health Status in Patients with Inflammatory Bowel Diseases: A Systematic Review. 2021 All outcomes | Up to 1 October 2021 | 16 | Not applicable |
Studies behind the findings
The primary studies the full-text reviews tie to this outcome. Reviews with headline outcomes only do not list them here.
- Increased risks of dental caries and periodontal disease in Chinese patients with inflammatory bowel disease. · 2020 · included by 1 of these review
- Active matrix metalloproteinase‐8 and periodontal bacteria—interlink between periodontitis and inflammatory bowel disease? · 2018 · included by 1 of these review
- Periodontitis and Gingivitis in Inflammatory Bowel Disease · 2013 · included by 1 of these review
- The association between inflammatory bowel disease and periodontitis among Jordanians: a case–control study · 2011 · included by 1 of these review
- Prevalence of periodontitis and DMFT index in patients with Crohn's disease and ulcerative colitis · 2008 · included by 1 of these review
- Prevalence of dental caries and periodontal disease in patients with inflammatory bowel disease: a case–control study · 2006 · included by 1 of these review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.