Area under the summary ROC curve · Patients undergoing dental caries detection on dental images (teeth/surfaces across imaging modalities)
The area under the summary ROC curve for AI caries detection is 0.86, indicating high overall diagnostic accuracy; ungraded.
1 finding from 1 review
Odds of higher caries (DMFT) category · 12-year-old children across European countries (national/regional epidemiological surveys, 2011-2022)
In the adjusted ordinal model geographical location was not independently significant for DMFT category (OR 0.57, 95% CI 0.24 to 1.35); not GRADE-rated.
1 finding from 1 review
Odds of higher caries (DMFT) category · 12-year-old children across European countries (national/regional epidemiological surveys, 2011-2022)
HDI was not independently associated with DMFT category in the adjusted model (OR 1.82, 95% CI 0.32 to 10.47); not GRADE-rated.
1 finding from 1 review
Positive likelihood ratio · Patients undergoing dental caries detection on dental images (teeth/surfaces across imaging modalities)
A positive AI test raises caries probability substantially (LR+ 10.44; positive post-test probability 79%); ungraded.
1 finding from 1 review
Log diagnostic odds ratio · Patients undergoing dental caries detection on dental images (teeth/surfaces across imaging modalities)
AI algorithms show strong pooled discriminative accuracy for dental caries (log DOR 4.37; DOR 70.9); ungraded.
1 finding from 1 review
Negative likelihood ratio · Patients undergoing dental caries detection on dental images (teeth/surfaces across imaging modalities)
A negative AI test lowers caries probability substantially (LR- 0.17; negative post-test probability 6%); ungraded.
1 finding from 1 review
Marginal adaptation (clinically detectable deterioration) · People with permanent posterior teeth restored with class I or II direct restorations
At 60 months, marginal adaptation did not differ significantly between the composites (4 groups; ungraded).
5 findings from 1 review
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Secondary caries · People with permanent posterior teeth restored with class I or II direct restorations
No secondary caries was reported at 24 months in any of seven studies, so no meta-analysis was possible (ungraded).
2 findings from 1 review
Marginal discoloration · People with permanent posterior teeth restored with class I or II direct restorations
At 24 months, marginal discoloration did not differ significantly (7 groups; p = 0.77; ungraded).
4 findings from 1 review
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Retention (restoration loss) · People with permanent posterior teeth restored with class I or II direct restorations
At 24 months, retention did not differ significantly between the composites (6 studies; ungraded).
2 findings from 1 review
Postoperative sensitivity · People with permanent posterior teeth restored with class I or II direct restorations
Postoperative sensitivity at 12 months did not differ significantly between low polymerization shrinkage and methacrylate composites (OR 1.65, 95% CI 0.71 to 3.81; Moderate certainty).
2 findings from 1 review
Effects of non-stevia high-intensity sweeteners (aspartame, sucralose, saccharin) on cariogenic bacteria in dental plaque or saliva · healthy people
No eligible studies evaluated high-intensity sweeteners such as aspartame, sucralose, or saccharin for their effect on cariogenic bacteria.
1 finding from 1 review
Change in Mutans streptococci (MS) count in saliva · healthy people
Xylitol significantly reduced Mutans streptococci in saliva compared with no intervention (SMD -1.47, 95% CI -1.94 to -0.99; 3 trials), though heterogeneity was very high (I2=98%); not GRADE-rated.
1 finding from 1 review
Change in Mutans streptococci (MS) count in saliva · healthy people
Xylitol and sorbitol did not differ significantly for Mutans streptococci in saliva (SMD -0.16, 95% CI -0.44 to 0.12; 2 trials, P=.25); not GRADE-rated.
1 finding from 1 review
Change in Mutans streptococci (MS) count in dental plaque · healthy people
Xylitol significantly reduced Mutans streptococci in dental plaque compared with no treatment (SMD -0.73, 95% CI -1.09 to -0.37; 5 trials, I2=53%; not GRADE-rated).
1 finding from 1 review
Change in Mutans streptococci (MS) count in dental plaque · healthy people
Xylitol reduced Mutans streptococci in dental plaque more than sorbitol (SMD -0.45, 95% CI -0.69 to -0.21; 4 trials, I2=7%); not GRADE-rated.
1 finding from 1 review
Oral health-related quality of life · Indians
In adolescents (10-19 years), dental caries was associated with poorer OHRQoL (pooled OR 3.92; 5 studies); ungraded.
5 findings from 1 review
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CA VI activity · Children (age about 2-9 years) across the 7 meta-analyzed activity samples; excludes Kivela 1999 adults (18-24 years), qualitative only…
Salivary/biofilm CA VI activity is significantly higher in individuals with dental caries than in caries-free individuals (SMD 0.894, 95% CI 0.386 to 1.392; not GRADE-rated).
1 finding from 1 review
Early childhood caries (ECC) - association at lead SNP rs76823412 (8:134690570; nearest gene(s) ST3GAL1) · Children up to age 5-6 years (European / European non-Hispanic ancestry); 843 ECC-affected vs 2124 unaffected across 5 cohorts (N=2974)
The common variant rs8091366 near CHST9, KCTD1 showed suggestive (not genome-wide significant) association with ECC (Z = 4.476, p = 7.60e-6); genetic association, ungraded.
2 findings from 1 review
Early childhood caries (ECC) - association at lead SNP rs563135 (10:115067899; nearest gene(s) TCF7L2, CASP7) · Children up to age 5-6 years (European / European non-Hispanic ancestry); 843 ECC-affected vs 2124 unaffected across 5 cohorts (N=2974)
The common variant rs563135 near TCF7L2, CASP7 showed suggestive (not genome-wide significant) association with ECC (Z = -4.532, p = 5.86e-6); genetic association, ungraded.
1 finding from 1 review