Findings

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Evidence found and GRADE certainty

4,411 questions · 5,986 findings · 226 reviews · Oral Health

No studies found 1,305 · 21.8%GRADE not reported 2,988 · 49.9%Very low 1,030 · 17.2%Low 476 · 8%Moderate 156 · 2.6%High 31 · 0.5%

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Endodontic therapy (surgical or non-surgical) performed with the aid of one or more magnification devices (surgical microscope, endoscope or magnifying loupes) vs The same endodontic therapy performed without magnification devices (without visual enhancers)

Total time required to complete the clinical procedure · Patients of any age who received endodontic therapy and were followed up for at least 1 year after treatment

The review found no eligible studies for this question.

1 finding from 1 review
  • Magnification devices for endodontic therapy 2015 · Cochrane All outcomes
    No included study assessed procedure time; such outcomes were only sporadically reported and were never statistically assessed.
    Studies not reported
    No studies found

Aversive tasting substance applied to digit vs Psychological intervention (habit reversal)

Sucking cessation (short term) · Children with a non-nutritive sucking habit (digit or pacifier)

Aversive tasting substance applied to digit showed no clear difference in sucking cessation (short term) compared with psychological intervention (habit reversal); GRADE not reported.

1 finding from 1 review

Tyrosine kinase inhibitor (erlotinib, gefitinib or lapatinib) plus standard therapy (radiotherapy or chemoradiotherapy) vs Standard therapy alone (radiotherapy or chemoradiotherapy)

Overall survival · People with squamous cell carcinoma of the oral cavity or oropharynx

It is very uncertain whether tyrosine kinase inhibitor (erlotinib, gefitinib or lapatinib) plus… changes overall survival compared with standard therapy alone (radiotherapy or chemoradiotherapy) (very low certainty).

1 finding from 1 review

Chlorhexidine gel (0.12%) vs no treatment

Pain, quality of life, patient satisfaction or costs · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…

The review found no eligible studies for this question.

1 finding from 1 review

Psychological intervention (habit reversal / positive reinforcement) vs Alternative psychological intervention (DRO / negative reinforcement)

Sucking cessation (short term) · Children with a non-nutritive sucking habit (digit or pacifier)
1 finding from 1 review
  • Interventions for the cessation of non‐nutritive sucking habits in children 2015 · Cochrane All outcomes
    Short term (less than 12 months)
    Christensen 1987 (20 participants) compared habit reversal (HR) with differential reinforcement of other behaviour (DRO): no statistically significant difference. Larsson 1972 (38 participants) compared positive with…
    2 studies · 58 participants
    GRADE not reported

Transplantation of other teeth after extraction of the ankylosed teeth vs Conventional orthodontic treatment or follow-up with no specific treatment for ankylosis

Outcome not reported · Any patient with ankylosis and displacement of permanent front teeth diagnosed by clinical and radiographic assessment, with or without…

The review found no eligible studies for this question.

1 finding from 1 review

Xylitol lozenges (5 g/day) vs placebo control

Adverse effects (sores in the mouth, cramps, bloating, constipation, flatulence, loose stool or diarrhoea) · adults
1 finding from 1 review

Xylitol tablets (200 to 600 mg/day) via slow-release pacifier/dummy vs Control (sorbitol) tablets

Number of infants with a caries increment (dmfs) · Infants (primary teeth)

It is very uncertain whether xylitol tablets (200 to 600 mg/day) via slow-release pacifier/dummy changes number of infants with a caries increment (dmfs) compared with control (sorbitol) tablets (very low certainty).

1 finding from 1 review

Fixed-appliance orthodontic treatment incorporating surgically assisted orthodontics (adjunctive surgical procedure: corticotomy, micro-osteoperforation or interseptal bone reduction) to increase the rate of tooth movement vs Conventional orthodontic appliance treatment

Prolonged stability of treatment (adjudged using an accepted scale) · Individuals of any age receiving orthodontic treatment with fixed appliances (braces) (people requiring orthodontic tooth movement);…

The review found no eligible studies for this question.

1 finding from 1 review

Cryotherapy (ice chips) 30 minutes vs Cryotherapy (ice chips) 60 minutes

Oral mucositis (severe) · Adults with solid cancers receiving fluorouracil (5FU) and leucovorin

It is very uncertain whether oral cryotherapy for 30 minutes changes oral mucositis (severe) compared with oral cryotherapy for 60 minutes (very low certainty).

1 finding from 1 review

Oral cryotherapy (ice chips, ice-cold water, ice cubes or crushed ice held in the mouth during cancer treatment) vs Chlorhexidine rinse

Oral mucositis (any severity) · Adults with solid cancers receiving fluorouracil (5FU) and leucovorin

It is very uncertain whether oral cryotherapy (ice chips, ice-cold water, ice cubes or crushed… changes oral mucositis (any severity) compared with chlorhexidine rinse (very low certainty).

1 finding from 1 review

Fixed-appliance orthodontic treatment incorporating surgically assisted orthodontics (adjunctive surgical procedure: corticotomy, micro-osteoperforation or interseptal bone reduction) to increase the rate of tooth movement vs Conventional orthodontic appliance treatment

Rate of orthodontic tooth movement with removable orthodontic aligners · Individuals of any age receiving orthodontic treatment with fixed appliances (braces) (people requiring orthodontic tooth movement);…

Fixed-appliance orthodontic treatment incorporating surgically… may leads to higher rate of tooth movement (orthodontic tooth movement in mm at 3 months) compared with conventional treatment: fixed-appliance orthodontic treatment… (low certainty).

2 findings from 1 review

Hall technique vs Non-restorative caries treatment

Discomfort associated with the procedure · Children with decayed primary molar teeth

It is very uncertain whether preformed metal crown (fitted using the Hall Technique) changes discomfort associated with the procedure compared with non-restorative caries treatment (very low certainty).

1 finding from 1 review

Oral cryotherapy (ice chips, ice-cold water, ice cubes or crushed ice held in the mouth during cancer treatment) vs Low-dose leucovorin rinse

Oral mucositis (any severity) · Patients with osteosarcoma (bone cancer) receiving high-dose methotrexate, vincristine and leucovorin

It is very uncertain whether oral cryotherapy (ice chips, ice-cold water, ice cubes or crushed… changes oral mucositis (any severity) compared with low-dose leucovorin rinse (very low certainty).

1 finding from 1 review