Cochrane · intervention · CD003876

Fluoridated milk for preventing dental caries

Yeung, CA, Chong, LY, Glenny, AM · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library

Oral HealthDental caries4 versionsAMSTAR 2: not assessed
Full textEvery question was extracted from the full review (methods and results), not only its Summary of Findings table.
Questions
6
current version
GRADE rated
2
No studies
4
Included studies
1
as reported
No studies 4 · 66.7%Ungraded 0 · 0%Very low 0 · 0%Low 2 · 33.3%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Review question

ElementPlanned (methods)Found (results)
PopulationGeneral population, irrespective of age or level of risk for dental caries180 children aged three years randomised; 166 available for analysis (Maslak 2004)
InterventionFluoridated milk (all concentrations/dosage)Fluoridated milk 2.5 mg/L, drunk from a cup (n=166)
ComparisonNon-fluoridated milkNon-fluoridated milk (n=166)
OutcomesPrimary: changes in caries experience/increment (DMFT/DMFS permanent, dmft/dmfs primary); Adverse effects: dental fluorosis; Secondary: dental pain due to decay; antibiotics due to dental infections; requirement for general anaesthesia for cariesDMFT 3 years (n=1); dmft 3 years (n=1); adverse effects/fluorosis: none reported (n=1); dental pain, antibiotics, general anaesthesia: no evidence found (n=0)
Study designsParallel RCT (cluster-randomised included; quasi-randomised excluded)Parallel RCT (n=1, Maslak 2004)
TimingIntervention or follow-up period of at least two years (or an equivalent of two school years)3 years follow-up

Search date: 2014-11. Databases: Cochrane Oral Health Group's Trials Register; CENTRAL; MEDLINE via OVID; EMBASE via OVID

Questions and results

Show all 4 versions

Fluoridated milk vs Non-fluoridated milk

Population: General population, irrespective of age or level of risk for dental caries
6 questions
OutcomeEffectEvidenceStatus / GRADE
Requirement for general anaesthesia due to dental procedures for caries
No evidence found. (No information was reported by the included study.)0 studiesNo studies
Adverse effects: dental fluorosis
No evidence found. (Correspondence with the author (Maslak 2004) confirmed that no adverse effects were reported.)0 studiesNo studies
Dental pain due to decay
No evidence found. (No information was reported by the included study.)0 studiesNo studies
Antibiotics due to dental infections
No evidence found. (No information was reported by the included study.)0 studiesNo studies
Caries in primary teeth: dmft (3 years)
3 years
MD -1.14 [-1.86, -0.42]
-1.14 [-1.86, -0.42] dmft (mean)
1 study · 166 participantsLow
Downgraded: risk of bias, indirectness
Caries in permanent teeth: DMFT (3 years)
3 years
MD -0.13 [-0.24, -0.02]
-0.13 [-0.24, -0.02] DMFT (mean)
1 study · 166 participantsLow
Downgraded: risk of bias, indirectness