Cochrane · intervention · CD010572

Surgical adjunctive procedures for accelerating orthodontic treatment

Fleming, PS, Fedorowicz, Z, Johal, A, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library

Oral HealthOrthodontics2 versionsAMSTAR 2: not assessed
Full textEvery question was extracted from the full review (methods and results), not only its Summary of Findings table.
Questions
8
current version
GRADE rated
3
No studies
4
Included studies
4
as reported
No studies 4 · 50%Ungraded 1 · 12.5%Very low 1 · 12.5%Low 2 · 25%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Review question

ElementPlanned (methods)Found (results)
PopulationIndividuals of any age receiving orthodontic treatment with fixed appliances (braces) (people requiring orthodontic tooth movement); participants treated with orthognathic surgery or with cleft lip or palate or other craniofacial deformity/syndrome excludedA total of 57 (15 male and 42 female) participants aged 11 to 33 years across 4 trials; mean age 19.2 years in the extraction space-closure study (Aboul-Ela 2011); adults only in the canine-retraction studies (Alikhani 2013; Leethanakul 2014); age range 11.1 to 12.9 years in the ectopic-canine study (Fischer 2007)
InterventionAny form of orthodontic treatment with fixed appliances, including extraction and non-extraction treatment with or without inter-proximal reduction (tooth size reduction), incorporating surgically assisted/accelerated orthodontics to increase the rate of tooth movementSurgical adjuncts: corticotomy (n=2: space closure, Aboul-Ela 2011; ectopic-canine alignment, Fischer 2007); micro-osteoperforations, repeated (n=1: Alikhani 2013); interseptal bone reduction (n=1: Leethanakul 2014)
ComparisonAny form of orthodontic treatment with fixed appliances, including extraction and non-extraction treatment with or without inter-proximal reduction, without use of surgically assisted/accelerated orthodonticsConventional fixed appliance-based orthodontic treatment without surgical assistance (n=4)
OutcomesPrimary: duration of orthodontic treatment, number of visits during active treatment (scheduled and unscheduled) and duration of visits; Secondary: harms arising during orthodontic treatment (gingival and periodontal problems, anchorage loss, iatrogenic damage to teeth e.g. caries/decalcification, root resorption); patient-reported/patient-centred outcomes (impact of fixed appliances on daily life, quality of life and pain experience); patient satisfaction (validated questionnaires or scales); improvement in occlusion (PAR or other validated scale); prolonged stability of treatmentRate of tooth movement (n=4); periodontal health and inflammatory response (n=1); pain experience (n=1); duration of orthodontic treatment not reported (n=0)
Study designsRandomised controlled trialsRandomised controlled trials (n=4; 2 split-mouth; all assessed at unclear risk of bias)
TimingNot specifiedFollow-up: one month (Alikhani 2013); three months of canine retraction (Leethanakul 2014); orthodontic space closure up to four months (Aboul-Ela 2011); until alignment of the ectopic canine tip (Fischer 2007)

Search date: 2014-09. Databases: Cochrane Oral Health Group's Trials Register; Cochrane Central Register of Controlled Trials (CENTRAL); MEDLINE via OVID; EMBASE via OVID; LILACS via BIREME; metaRegister of Controlled Trials (mRCT); ClinicalTrials.gov (US NIH Register); WHO International Clinical Trials Registry Platform (ICTRP)

Questions and results

Show all 2 versions

Fixed-appliance orthodontic treatment incorporating surgically assisted orthodontics (adjunctive surgical procedure: corticotomy, micro-osteoperforation or interseptal bone reduction) to increase the rate of tooth movement vs Conventional treatment: fixed-appliance orthodontic treatment without surgical assistance

Population: Individuals of any age receiving orthodontic treatment with fixed appliances (braces) (people requiring orthodontic tooth movement); participants treated with orthognathic surgery or with cleft lip or palate or other craniofacial deformity/syndrome excluded
8 questions
OutcomeEffectEvidenceStatus / GRADE
Prolonged stability of treatment (adjudged using an accepted scale)
Results: 'Our prespecified secondary outcomes of patient satisfaction, improvement in occlusion, and prolonged stability of treatment were not measured in the trials.'0 studiesNo studies
Patient satisfaction (measured using validated questionnaires or scales)
Results: 'Our prespecified secondary outcomes of patient satisfaction, improvement in occlusion, and prolonged stability of treatment were not measured in the trials.'0 studiesNo studies
Rate of tooth movement (orthodontic tooth movement in mm at 3 months)
3 months
MD 2.03 [1.52, 2.54]
The mean orthodontic movement in the control groups was 3.0 mm (median of the two control-group means, 2.54 and 3.4…
2 studies · 31 participantsLow
Downgraded: risk of bias, indirectness
Duration of orthodontic treatment, number of visits during active treatment (scheduled and unscheduled) and duration of visits
SoF row: Illustrative comparative risks '‐' / '‐'; no relative effect; Comments: 'Not reported'. Results: 'Our prespecified primary outcome (the duration of orthodontic treatment, number of visits during active…0 studiesNo studies
Harms arising during orthodontic treatment (gingival and periodontal problems, anchorage loss and iatrogenic damage to teeth e.g. caries/decalcification, root resorption); only periodontal/gingival health assessed
Up to 4 months
SoF: Assumed risk 'See comment'; Corresponding risk 'See comment'; 13 (1 study, split‐mouth); Quality ⊕⊖⊖⊖ very low. Comment: 'Gingival and periodonal problems only were assesed in 1 study (Aboul‐Ela 2011). No precise…
See comment vs See comment
1 study · 13 participantsVery low
Downgraded: risk of bias, imprecision
Patient-reported outcome: pain experience (discomfort)
24 hours to 28 days
Results: 'Pain experience was compared between surgical and non‐surgical cases in a single study (Alikhani 2013). Within 24 hours of appliance activation and canine retraction, both groups reported higher levels of…1 studyUngraded
Rate of tooth movement (orthodontic tooth movement in mm at 1 month)
1 month
MD 0.61 [0.49, 0.72]3 studies · 42 participantsLow
Downgraded: risk of bias, indirectness
Improvement in occlusion (Peer Assessment Rating (PAR) or other validated scale)
Results: 'Our prespecified secondary outcomes of patient satisfaction, improvement in occlusion, and prolonged stability of treatment were not measured in the trials.'0 studiesNo studies