Question · asked by 1 review
Xylitol lozenges (5 g/day) vs placebo control: Adverse effects (sores in the mouth, cramps, bloating, constipation, flatulence, loose stool or diarrhoea)
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Xylitol lozenges (5 g/day) vs Control lozenges (sucralose-sweetened placebo, no xylitol) Adverse effects (sores in the mouth, cramps, bloating, constipation, flatulence, loose stool or diarrhoea) · Adults · 33 months Xylitol‐containing products for preventing dental caries in children and adults (2015) · Cochrane All outcomes | Patterns of adverse effects (sores in the mouth, cramps, bloating, constipation, flatulence, and loose stool or diarrhoea) were similar for both groups. Bader 2013. | 1 study · 669 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Xylitol‐containing products for preventing dental caries in children and adults 2015 · Cochrane All outcomes | 2014-08 | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.