Findings

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Evidence found and GRADE certainty

3,535 questions · 3,601 findings · 252 reviews · Pregnancy and Childbirth

No studies found 726 · 20.2%GRADE not reported 421 · 11.7%Very low 828 · 23%Low 993 · 27.6%Moderate 486 · 13.5%High 147 · 4.1%

(7.1) PGE2 (controlled release) vs all PGE2 delivery systems (all women)

Vaginal delivery not achieved within 24 hours · patients with induction of labour at term

(7.1) PGE2 (controlled release) showed no clear difference in vaginal delivery not achieved within 24 hours compared with all PGE2 delivery systems (all women) (moderate certainty).

1 finding from 1 review

(7.1) PGE2 (controlled release) vs all PGE2 delivery systems (all women)

Uterine hyperstimulation with fetal heart rate changes · patients with induction of labour at term

(7.1) PGE2 (controlled release) showed no clear difference in uterine hyperstimulation with FHR changes compared with all PGE2 delivery systems (all women) (moderate certainty).

1 finding from 1 review

(7.1) PGE2 (controlled release) vs all PGE2 delivery systems (all women)

Serious neonatal morbidity or perinatal death · patients with induction of labour at term

(7.1) PGE2 (controlled release) showed no clear difference in serious neonatal morbidity or perinatal death compared with all PGE2 delivery systems (all women) (low certainty).

1 finding from 1 review

Chlorhexidine (vaginal wash or gel/cream) vs placebo or no treatment

Early onset GBS disease (sepsis and/or meningitis within the first seven days of life)) · women with vaginal or rectal colonization with GBS during labour and their preterm/term infants

It is very uncertain whether chlorhexidine (vaginal wash or gel/cream) changes early onset GBS disease (sepsis and/or meningitis within the first… compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Chlorhexidine (vaginal wash or gel/cream) vs placebo or no treatment

GBS pneumonia within the first seven days of life · women with vaginal or rectal colonization with GBS during labour and their preterm/term infants

It is very uncertain whether chlorhexidine (vaginal wash or gel/cream) changes GBS pneumonia within the first seven days of life compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Chlorhexidine (vaginal wash or gel/cream) vs placebo or no treatment

Neonatal colonization with GBS within the first seven days of life · women with vaginal or rectal colonization with GBS during labour and their preterm/term infants

It is very uncertain whether chlorhexidine (vaginal wash or gel/cream) changes neonatal colonization with GBS within the first seven days of life compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Chlorhexidine (vaginal wash or gel/cream) vs placebo or no treatment

Adverse (mild) effects in the mother · women with vaginal or rectal colonization with GBS during labour and their preterm/term infants

It is very uncertain whether chlorhexidine (vaginal wash or gel/cream) changes adverse (mild) effects in the mother compared with placebo or no treatment (very low certainty).

1 finding from 1 review