Question · asked by 1 review
PGE2 vs placebo or no treatment: Serious maternal morbidity or death
- Population
- patients with induction of labour at term
- Intervention
- PGE2
- Comparison
- placebo or no treatment
- Outcome
- Serious maternal morbidity or death
It is very uncertain whether PGE2 changes serious maternal morbidity or death compared with placebo or no treatment (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
PGE2 vs placebo or no treatment Serious maternal morbidity or death · patients with induction of labour at term It is very uncertain whether PGE2 changes serious maternal morbidity or death compared with placebo or no treatment (very low certainty). Vaginal prostaglandin (PGE2 and PGF2a) for induction of labour at term (2014) · Cochrane Headline outcomes only | RR 2.23 [0.34, 14.76] | 3 studies · 530 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Vaginal prostaglandin (PGE2 and PGF2a) for induction of labour at term 2014 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.