PGE2 vs placebo or no treatment: Serious neonatal morbidity or perinatal death
PGE2 showed no clear difference in serious neonatal morbidity or perinatal death compared with placebo or no treatment (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
PGE2 vs placebo or no treatment Serious neonatal morbidity or perinatal death · patients with induction of labour at term PGE2 showed no clear difference in serious neonatal morbidity or perinatal death compared with placebo or no treatment (low certainty). Vaginal prostaglandin (PGE2 and PGF2a) for induction of labour at term (2014) · Cochrane Headline outcomes only | RR 0.46 [0.09, 2.31] | 9 studies · 3638 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Vaginal prostaglandin (PGE2 and PGF2a) for induction of labour at term 2014 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.