Findings

What do systematic reviews say?

2,973 questions · 3,072 findings · 410 reviews · Headline outcomes only

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No studies found 559 · 18.2%GRADE not reported 143 · 4.7%Very low 654 · 21.3%Low 833 · 27.1%Moderate 683 · 22.2%High 200 · 6.5%

Micropulse vs continuous‐wave cyclophotocoagulation

Adverse events 12 months postintervention · adults with refractory glaucoma

1 finding from 1 review

Cyclodestructive procedures for refractory glaucoma 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 46 participants
GRADE not reported

Micropulse vs continuous‐wave cyclophotocoagulation

Mean change in quality of life scores 12 months postintervention · adults with refractory glaucoma

The review found no eligible studies for this question.

1 finding from 1 review

Cyclodestructive procedures for refractory glaucoma 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Micropulse vs continuous‐wave cyclophotocoagulation

Pain control · adults with refractory glaucoma

1 finding from 1 review

Cyclodestructive procedures for refractory glaucoma 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 44 participants
GRADE not reported

Micropulse vs continuous‐wave cyclophotocoagulation

Mean change in IOP measured in mmHg 12 months postintervention · adults with refractory glaucoma

1 finding from 1 review

Cyclodestructive procedures for refractory glaucoma 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 48 participants
GRADE not reported

Intervention not reported

Head impulse

1 finding from 1 review

Head impulse, nystagmus, and test of skew examination for diagnosing central causes of acute vestibular syndrome 2023 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 905 participants
Low

Intervention not reported

Video head impulse

1 finding from 1 review

Head impulse, nystagmus, and test of skew examination for diagnosing central causes of acute vestibular syndrome 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 239 participants
Very low

Summary of findings: Inhaled antibiotics vs IV antibiotics

Time to next pulmonary exacerbation · adults and children with cystic fibrosis (during acute exacerbations of lung disease)

1 finding from 1 review

Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 59 participants
Very low

Intervention not reported

Proportion of patients with COPD referred to, participating in or having completed pulmonary rehabilitation · health professionals managing COPD

1 finding from 1 review

Educational interventions for health professionals managing chronic obstructive pulmonary disease in primary care 2022 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 625 participants
Low

Thrombolytic therapy vs heparin: primary outcome measures

Recurrence of pulmonary emboli · patients with acute pulmonary embolism

Thrombolytic therapy may leads to lower recurrence of pulmonary emboli (duration of compared with heparin: primary outcome measures (low certainty).

1 finding from 1 review

Thrombolytic therapy for pulmonary embolism 2021 · Cochrane Headline outcomes only
OR 0.54 [0.32, 0.91]
12 studies · 2050 participants
Low

Intervention not reported

Index test, population · people living with HIV and non‐hospitalized people in high‐risk groups

The review found no eligible studies for this question.

1 finding from 1 review

Xpert MTB/RIF and Xpert Ultra assays for screening for pulmonary tuberculosis and rifampicin resistance in adults,… 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Retrievable vena caval filters with anticoagulation vs anticoagulation

Recurrent PE · participants with unprovoked acute symptomatic PE and at high risk for recurrent PEa

Retrievable vena caval filters with anticoagulation showed no clear difference in PE: recurrent fatal and non‐fatal PE, demonstrated by CT, pulmonary… compared with anticoagulation (moderate certainty).

1 finding from 1 review

Vena caval filters for the prevention of pulmonary embolism 2020 · Cochrane Headline outcomes only
RR 1.74 [0.52, 5.86]
1 study · 399 participants
Moderate

Retrievable vena caval filters with anticoagulation vs anticoagulation

Recurrent PE · participants who sustained multiple traumatic injuriesa

1 finding from 1 review

Vena caval filters for the prevention of pulmonary embolism 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 80 participants
Moderate

Summary of findings: β‐carotene vs placebo

Number of days on antibiotics for acute exacerbations · adults and children with cystic fibrosis

Summary of findings: β‐carotene showed no clear difference in pulmonary exacerbations Days of antibiotic use compared with placebo (low certainty).

1 finding from 1 review

Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 24 participants
Low

Summary of findings: monoclonal antibody KB001‐A vs placebo

Pulmonary exacerbations · children (12 or over) and adults with cystic fibrosis and lung infection

Summary of findings: monoclonal antibody KB001‐A showed no clear difference in pulmonary exacerbations compared with placebo (low certainty).

1 finding from 1 review

Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis 2020 · Cochrane Headline outcomes only
RR 0.25 [0.03, 2.4]
2 studies · 196 participants
Low

Summary of findings: nitric oxide vs placebo

Pulmonary exacerbations · children (12 or over) and young adults with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Zinc vs placebo

Pulmonary exacerbations number of participants requiring IV antibiotics · children with cystic fibrosis

Summary of findings: Zinc supplementation showed no clear difference in pulmonary exacerbations number of participants requiring IV… compared with placebo (moderate certainty).

1 finding from 1 review

Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis 2020 · Cochrane Headline outcomes only
RR 1.85 [0.65, 5.26]
1 study · 37 participants
Moderate

Summary of findings: β‐carotene vs placebo

Need for antibiotics see pulmonary exacerbations · adults and children with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oxygen‐guided lung‐recruitment maneuver vs usual care

Bronchopulmonary dysplasia · preterm infants < 37 weeks' gestational age requiring conventional mechanical ventilation for respiratory distress syndrome

Oxygen‐guided lung‐recruitment maneuver showed no clear difference in bronchopulmonary dysplasia compared with routine care (low certainty).

1 finding from 1 review

Positive end‐expiratory pressure for preterm infants requiring conventional mechanical ventilation for respiratory… 2019 · Cochrane Headline outcomes only
RR 0.25 [0.03, 2.07]
2 studies · 44 participants
Low

NIPPV vs no NIPPV

Pulmonary complications (0 to 30 days) · Patients with lung cancer

NIPPV showed no clear difference in pulmonary complications compared with no NIPPV (low certainty).

1 finding from 1 review

Non‐invasive positive pressure ventilation for prevention of complications after pulmonary resection in lung cancer… 2019 · Cochrane Headline outcomes only
RR 1.03 [0.72, 1.47]
4 studies · 238 participants
Low

Alpha‐blockers vs placebo

Stone expulsion time · adult patients presenting with symptoms of ureteral stone disease

1 finding from 1 review

Alpha‐blockers as medical expulsive therapy for ureteral stones 2018 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 3240 participants
Low