Cochrane · systematic review · CD004500
Positive end‐expiratory pressure for preterm infants requiring conventional mechanical ventilation for respiratory distress syndrome or bronchopulmonary dysplasia
Bamat, N, Fierro, J, Wang, Y, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library
NeonatalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 100%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Oxygen‐guided lung‐recruitment maneuver compared to routine care for individualizing PEEP to an optimal level in preterm infants requiring conventional mechanical ventilation for respiratory distress syndrome (objective 3)
Population: preterm infants < 37 weeks' gestational age requiring conventional mechanical ventilation for respiratory distress syndrome
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality by hospital discharge Oxygen‐guided lung‐recruitment maneuver vs routine care | RR 1 [0.17, 5.77] | 2 studies · 44 participants | Low Downgraded: risk of bias, imprecision |
Bronchopulmonary dysplasia Oxygen‐guided lung‐recruitment maneuver vs routine care | RR 0.25 [0.03, 2.07] | 2 studies · 44 participants | Low Downgraded: risk of bias, imprecision |
Duration of invasive ventilatory support Oxygen‐guided lung‐recruitment maneuver vs routine care | no estimate extracted | 2 studies · 44 participants | Low Downgraded: risk of bias, imprecision, inconsistency |