Cochrane · systematic review · CD012223

Cyclodestructive procedures for refractory glaucoma

Chen, MF, Kim, CH, Coleman, AL · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library

Eyes and VisionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
28
current version
GRADE rated
9
No studies
12
Included studies
NR
No studies 12 · 42.9%Ungraded 7 · 25%Very low 7 · 25%Low 2 · 7.1%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Endoscopic cyclophotocoagulation compared with the Ahmed drainage implant for refractory glaucoma

Population: adults with refractory glaucoma
7 questions
OutcomeEffectEvidenceStatus / GRADE
Pain control change from baseline 12 months postintervention
Endoscopic cyclophotocoagulation vs the Ahmed drainage implant
no estimate extractedNRNo studies
Mean change in IOP measured in mmHg 12 months postintervention
Endoscopic cyclophotocoagulation vs the Ahmed drainage implant
no estimate extracted1 study · 58 participantsLow
Downgraded: risk of bias, imprecision
Mean change in best‐corrected visual acuity measured by logMAR 12 months postintervention
Endoscopic cyclophotocoagulation vs the Ahmed drainage implant
no estimate extracted1 study · 54 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Mean change in mean deviation in study eyes 12 months postintervention
Endoscopic cyclophotocoagulation vs the Ahmed drainage implant
no estimate extractedNRNo studies
Mean number of glaucoma medications 12 months postintervention
Endoscopic cyclophotocoagulation vs the Ahmed drainage implant
no estimate extracted1 study · 54 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Adverse events 12 months postintervention
Endoscopic cyclophotocoagulation vs the Ahmed drainage implant
no estimate extracted1 study · 68 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Mean change in quality of life scores 12 months postintervention
Endoscopic cyclophotocoagulation vs the Ahmed drainage implant
no estimate extractedNRNo studies

Micropulse versus continuous‐wave cyclophotocoagulation for refractory glaucoma

Population: adults with refractory glaucoma
7 questions
OutcomeEffectEvidenceStatus / GRADE
Pain control change from baseline 12 months postintervention
Micropulse vs continuous‐wave cyclophotocoagulation
no estimate extracted1 study · 44 participantsUngraded
Mean change in IOP measured in mmHg 12 months postintervention
Micropulse vs continuous‐wave cyclophotocoagulation
no estimate extracted1 study · 48 participantsUngraded
Mean change in best‐corrected visual acuity measured by logMAR 12 months postintervention
Micropulse vs continuous‐wave cyclophotocoagulation
no estimate extracted1 study · 48 participantsUngraded
Mean change in the mean deviation in study eyes change from baseline 12 months postintervention
Micropulse vs continuous‐wave cyclophotocoagulation
no estimate extractedNRNo studies
Mean number of glaucoma medications 12 months postintervention
Micropulse vs continuous‐wave cyclophotocoagulation
no estimate extracted1 study · 46 participantsUngraded
Adverse events 12 months postintervention
Micropulse vs continuous‐wave cyclophotocoagulation
no estimate extracted1 study · 46 participantsUngraded
Mean change in quality of life scores 12 months postintervention
Micropulse vs continuous‐wave cyclophotocoagulation
no estimate extractedNRNo studies

Comparison of two cyclophotocoagulation lasers for refractory glaucoma

Population: adults with refractory glaucoma
7 questions
OutcomeEffectEvidenceStatus / GRADE
Pain control change from baseline 12 months postintervention
no estimate extractedNRNo studies
Mean change in IOP measured in mmHg 12 months postintervention
no estimate extracted1 study · 95 participantsLow
Downgraded: risk of bias, imprecision
Mean change in best‐corrected visual acuity measured by logMAR 12 months postintervention
no estimate extracted2 studies · 127 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Mean change in the mean deviation in study eyes change from baseline 12 months postintervention
no estimate extractedNRNo studies
Mean number of glaucoma medications 12 months postintervention
no estimate extractedNRNo studies
Adverse events 12 months postintervention
no estimate extractedNRNo studies
Mean change in quality of life scores 12 months postintervention
no estimate extractedNRNo studies

Comparison of two cyclophotocoagulation energy levels for refractory glaucoma

Population: adults with refractory glaucoma
7 questions
OutcomeEffectEvidenceStatus / GRADE
Pain control change from baseline 12 months postintervention
no estimate extracted1 study · 50 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Mean change in IOP measured in mmHg 12 months postintervention
no estimate extracted1 study · 89 participantsUngraded
Mean change in best‐corrected visual acuity measured by logMAR 12 months postintervention
no estimate extracted1 study · 60 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Mean change in the mean deviation in study eyes change from baseline 12 months postintervention
no estimate extractedNRNo studies
Mean number of glaucoma medications 12 months postintervention
no estimate extracted1 study · 50 participantsVery low
Downgraded: risk of bias, imprecision, indirectness
Adverse events 12 months postintervention
no estimate extracted1 study · 50 participantsUngraded
Mean change in quality of life scores 12 months postintervention
no estimate extractedNRNo studies