Cochrane · systematic review · CD015089

Head impulse, nystagmus, and test of skew examination for diagnosing central causes of acute vestibular syndrome

Gottlieb, M, Peksa, GD, Carlson, JN · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library

StrokeAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
11
current version
GRADE rated
9
No studies
1
Included studies
NR
No studies 1 · 9.1%Ungraded 1 · 9.1%Very low 2 · 18.2%Low 3 · 27.3%Moderate 4 · 36.4%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

What is the diagnostic accuracy of HINTS and HINTS Plus for diagnosing a central cause of acute vestibular syndrome?

11 questions
OutcomeEffectEvidenceStatus / GRADE
Clinical HINTS
no estimate extracted12 studies · 1890 participantsLow
Downgraded: imprecision, inconsistency
Video‐assisted HINTS
no estimate extracted3 studies · 199 participantsVery low
Downgraded: imprecision, inconsistency
Clinical HINTS Plus
no estimate extracted5 studies · 451 participantsLow
Downgraded: imprecision, inconsistency
Video‐assisted HINTS Plus
no estimate extracted2 studies · 163 participantsModerate
Downgraded: imprecision
Secondary objectives for HINTS subcomponents
no estimate extractedNRNo studies
Head impulse
no estimate extracted9 studies · 905 participantsLow
Downgraded: imprecision, inconsistency
Video head impulse
no estimate extracted3 studies · 239 participantsVery low
Downgraded: imprecision, inconsistency
Nystagmus
no estimate extracted9 studies · 1128 participantsModerate
Downgraded: imprecision, inconsistency
Test of skew
no estimate extracted10 studies · 1313 participantsModerate
Downgraded: imprecision, inconsistency
Investigation of heterogeneity and sensitivity analyses
no estimate extracted95 participantsModerate
Downgraded: imprecision, inconsistency
Conclusions
no estimate extracted94 participantsUngraded