Question · asked by 1 review
Zinc vs placebo: Pulmonary exacerbations number of participants requiring IV antibiotics
- Population
- children with cystic fibrosis
- Intervention
- Zinc
- Comparison
- placebo
- Outcome
- Pulmonary exacerbations number of participants requiring IV antibiotics
Summary of findings: Zinc supplementation showed no clear difference in pulmonary exacerbations number of participants requiring IV… compared with placebo (moderate certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Summary of findings: Zinc supplementation vs placebo Pulmonary exacerbations number of participants requiring IV antibiotics · children with cystic fibrosis Summary of findings: Zinc supplementation showed no clear difference in pulmonary exacerbations number of participants requiring IV… compared with placebo (moderate certainty). Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis (2020) · Cochrane Headline outcomes only | RR 1.85 [0.65, 5.26] | 1 study · 37 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Antibiotic adjuvant therapy for pulmonary infection in cystic fibrosis 2020 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.