Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,087 questions · 2,360 findings · 390 reviews

No studies found 224 · 9.5%GRADE not reported 603 · 25.6%Very low 555 · 23.5%Low 548 · 23.2%Moderate 312 · 13.2%High 118 · 5%

Intervention not reported

Early embryo transfer ‐ G2 (specific) versus Ham's F10 (other) · Women in assisted reproductive technology cycles (ART) receiving human pre‐implantation embryos in either early (cleavage stage transfer)…

It is very uncertain whether the intervention changes early embryo transfer ‐ G2 (specific) versus Ham's F10 (other) (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Early amino acids vs Late amino acids

Growth during the first month of life · preterm born neonates
3 findings from 1 review

Summary of findings table ‐ Early amino acids vs Late amino acids

Neurodevelopmental outcomes · preterm born neonates

Summary of findings table ‐ Early amino acids showed no clear difference in neurodevelopmental outcome assessed by any standard tool compared with late amino acids (low certainty).

1 finding from 1 review

Early discontinuation of antibiotic treatment vs treatment until neutropenia resolution

All‐cause mortality · febrile neutropenia

Early discontinuation of antibiotic treatment showed no clear difference in mortality compared with treatment until neutropenia resolution (low certainty).

1 finding from 1 review

Early discontinuation of antibiotic treatment vs treatment until neutropenia resolution

Clinical failure · febrile neutropenia

It is very uncertain whether early discontinuation of antibiotic treatment changes clinical failure compared with treatment until neutropenia resolution (very low certainty).

1 finding from 1 review

Early discontinuation of antibiotic treatment vs treatment until neutropenia resolution

Bacteraemia · febrile neutropenia

It is very uncertain whether early discontinuation of antibiotic treatment changes any bacteraemia compared with treatment until neutropenia resolution (very low certainty).

1 finding from 1 review

Extended specialised early intervention (SEI) teams vs standard SEI teams plus treatment

Global state: recovery (assessed by symptom remission over a specified time period, as defined by study) · recent‐onset psychosis

It is very uncertain whether extended specialised early intervention (SEI) teams changes global state: recovery (assessed by symptom remission over a… compared with standard SEI teams plus treatment (very low certainty).

1 finding from 1 review

Extended specialised early intervention (SEI) teams vs standard SEI teams plus treatment

Service use: disengagement from services(assessment varied) · recent‐onset psychosis

Extended specialised early intervention (SEI) teams may leads to lower service use: disengagement from services(assessment varied) compared with standard SEI teams plus treatment (low certainty).

1 finding from 1 review

Extended specialised early intervention (SEI) teams vs standard SEI teams plus treatment

Service use: admission to psychiatric hospital (assessed by proportion admitted at end of treatment) · recent‐onset psychosis

Extended specialised early intervention (SEI) teams showed no clear difference in service use: admission to psychiatric hospital at end of treatment… compared with standard SEI teams plus treatment (low certainty).

1 finding from 1 review

Extended specialised early intervention (SEI) teams vs standard SEI teams plus treatment

Adverse effects/events: death ‐ all‐cause mortality(assessed by patient records) · recent‐onset psychosis

Extended specialised early intervention (SEI) teams showed no clear difference in adverse effects/events: death ‐ all‐cause mortality(assessed by… compared with standard SEI teams plus treatment (low certainty).

1 finding from 1 review