Cochrane · systematic review · CD007876

Culture media for human pre‐implantation embryos in assisted reproductive technology cycles

Youssef, MMA, Mantikou, E, van Wely, M, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library

Gynaecology and FertilityAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
9
current version
GRADE rated
8
No studies
1
Included studies
NR
No studies 1 · 11.1%Ungraded 0 · 0%Very low 7 · 77.8%Low 1 · 11.1%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Live birth or ongoing pregnancy per woman

Population: Women in assisted reproductive technology cycles (ART) receiving human pre‐implantation embryos in either early (cleavage stage transfer) or late (blastocyst stage transfer) stages
9 questions
OutcomeEffectEvidenceStatus / GRADE
Comparisons**
no estimate extractedNRNo studies
Early embryo transfer ‐ GM501 (specific) versus ISMI (other)
OR 1.03 [0.53, 2.03]1 study · 172 participantsVery low
Downgraded: risk of bias, imprecision
Early embryo transfer ‐ GM501 (specific) versus Sydney IVF (other)
OR 0.87 [0.38, 1.96]1 study · 158 participantsVery low
Downgraded: risk of bias, imprecision
Early embryo transfer ‐ G2 (specific) versus Universal IVF (other)
OR 1.53 [0.67, 3.51]1 study · 129 participantsVery low
Downgraded: risk of bias, imprecision
Early embryo transfer: Cook (K‐SIFM or K‐SICM) (specific) versus Vitrolife (IVF or G3) (other)
OR 0.98 [0.63, 1.54]1 study · 449 participantsLow
Downgraded: risk of bias, imprecision
Early embryo transfer ‐ G2 (specific) versus Ham's F10 (other)
OR 1.52 [0.58, 3.99]1 study · 72 participantsVery low
Downgraded: risk of bias, imprecision
Late embryo transfer ‐ GM501 (specific) versus Sydney IVF (other)
OR 0.67 [0.03, 14.03]1 study · 12 participantsVery low
Downgraded: risk of bias, imprecision
Late embryo transfer ‐ G2 (specific) versus Universal IVF (other)
OR 1.92 [0.44, 8.31]1 study · 47 participantsVery low
Downgraded: risk of bias, imprecision
Late embryo transfer ‐ ECM/Multiblast (specific) versus Global (other)
OR 0.5 [0.2, 1.26]1 study · 79 participantsVery low
Downgraded: risk of bias, imprecision