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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

75,239 questions in 5,342 reviews

current versions
No studies 15,213 · 20.2%Ungraded 10,323 · 13.7%Very low 17,528 · 23.3%Low 17,951 · 23.9%Moderate 11,190 · 14.9%High 3,034 · 4%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Intervention NR
Hostility BPRS hostility sub scale, CPRS hostility subscale, Q‐sort, speech content analysis (endpoints fall between 1 and 6 months) · Any individual experiencing recurrent aggressive outbursts or episodes
Antiepileptics for aggression and associated impulsivity (2010) · Cochrane
no estimate extracted4 studies · 143 participantsLow
Intervention NR
Anger Self‐reported outbursts, Rosenweig Picture Frustration Test (endpoints fall between 2 weeks and 6 months) · Any individual experiencing recurrent aggressive outbursts or episodes
Antiepileptics for aggression and associated impulsivity (2010) · Cochrane
no estimate extracted2 studies · 46 participantsLow
Intervention NR
Anger‐Hostility POMS anger‐hostility subscale (endpoints fall between 1 and 6 months) · Any individual experiencing recurrent aggressive outbursts or episodes
Antiepileptics for aggression and associated impulsivity (2010) · Cochrane
no estimate extracted3 studies · 125 participantsLow
Intervention NR
Non‐compliance leaving the study early (endpoints fall between 1 and 6 months) · Any individual experiencing recurrent aggressive outbursts or episodes
Antiepileptics for aggression and associated impulsivity (2010) · Cochrane
no estimate extracted6 studies · 411 participantsModerate
Intervention NR
Adverse events, any (endpoints fall between 1 6 six months) · Any individual experiencing recurrent aggressive outbursts or episodes
Antiepileptics for aggression and associated impulsivity (2010) · Cochrane
no estimate extracted3 studies · 300 participantsModerate
Orientation & Mobility training vs physical exercise
Total score (using structured skills assessment) · patients with adults with low vision
Orientation and mobility training for adults with low vision (2010) · Cochrane
no estimate extracted2 studies · 67 participantsVery low
Intervention NR
All clinical conditions (binary outcomes)
Placebo interventions for all clinical conditions (2010) · Cochrane
no estimate extracted44 studies · 6041 participantsModerate
Intervention NR
All clinical conditions (continuous outcomes)
Placebo interventions for all clinical conditions (2010) · Cochrane
no estimate extracted158 studies · 10525 participantsModerate
Intervention NR
Pain [2] (continuous outcomes)
Placebo interventions for all clinical conditions (2010) · Cochrane
no estimate extracted60 studies · 4154 participantsModerate
Intervention NR
Nausea [2] (continuous outcomes) Â
Placebo interventions for all clinical conditions (2010) · Cochrane
no estimate extracted7 studies · 452 participantsModerate
Intervention NR
Depression [2] (continuous outcomes)
Placebo interventions for all clinical conditions (2010) · Cochrane
no estimate extracted8 studies · 324 participantsModerate
Intervention NR
Other outcomes [2] (continuous outcomes) Smoking, dementia, obesity, hypertension, insomnia, anxiety, asthma, phobia)
Placebo interventions for all clinical conditions (2010) · Cochrane
no estimate extracted41 studies · 1317 participantsLow
LHWs to promote immunisation uptake in children vs usual care
Immunisation schedule up to date Interviews with mothers, record reviews · patients with improving immunisation uptake among children < 2 years whose vaccination is not up to date
Lay health workers in primary and community health care for maternal and child health and the management of… (2010) · Cochrane
RR 1.22 [1.1, 1.37]4 studies · 3568 participantsModerate
Intervention NR
Completed preventive therapy with Isoniazid ‐ LHW supported self‐supervision or DOT compared with self‐supervision · patients with tuberculosis (TB) treatment
Lay health workers in primary and community health care for maternal and child health and the management of… (2010) · Cochrane
RR 1 [0.92, 1.09]2 studies · 595 participantsModerate
LHW support vs conventional support or care
Initiation of breastfeeding Self‐report · patients with breastfeeding
Lay health workers in primary and community health care for maternal and child health and the management of… (2010) · Cochrane
RR 1.36 [1.14, 1.61]12 studies · 17159 participantsModerate
LHW support vs conventional support or care
Any breastfeeding Self‐report · patients with breastfeeding
Lay health workers in primary and community health care for maternal and child health and the management of… (2010) · Cochrane
RR 1.24 [1.1, 1.39]12 studies · 8104 participantsModerate
LHW support vs conventional support or care
Exclusive breastfeeding Self‐report · patients with breastfeeding
Lay health workers in primary and community health care for maternal and child health and the management of… (2010) · Cochrane
RR 2.78 [1.74, 4.44]10 studies · 4334 participantsModerate
LHWs vs usual care
Mortality among children less than 5 years Verbal autopsy · patients with reducing mortality and morbidity in children <5 years
Lay health workers in primary and community health care for maternal and child health and the management of… (2010) · Cochrane
RR 0.75 [0.55, 1.03]3 studies · 56378 participantsLow
LHWs vs usual care
Morbidity e.g. fever, diarrhoea, ARI Verbal reports obtained during home visits, record reviews · patients with reducing mortality and morbidity in children <5 years
Lay health workers in primary and community health care for maternal and child health and the management of… (2010) · Cochrane
RR 0.86 [0.75, 0.99]7 studies · 17408 participantsLow
LHWs vs usual care
Neonatal Mortality verbal autopsy · patients with reducing mortality and morbidity in children <5 years
Lay health workers in primary and community health care for maternal and child health and the management of… (2010) · Cochrane
RR 0.76 [0.57, 1.02]4 studies · 29217 participantsLow
LHWs vs usual care
Morbidity ‐ care seeking practice hospital record review · patients with reducing mortality and morbidity in children <5 years
Lay health workers in primary and community health care for maternal and child health and the management of… (2010) · Cochrane
RR 1.33 [0.86, 2.05]3 studies · 11195 participantsLow
Intervention NR
Cure for smear positive TB patients (new and retreatment) Sputum smear test · patients with tuberculosis (TB) treatment
Lay health workers in primary and community health care for maternal and child health and the management of… (2010) · Cochrane
RR 1.22 [1.13, 1.31]4 studies · 1203 participantsModerate
Intervention NR
asteric* denotes studies reporting both speed and crash outcomes.
Speed cameras for the prevention of road traffic injuries and deaths (2010) · Cochrane
no estimate extractedNRNo studies
Intervention NR
A time halo effect lasted for 3 days following a single application of enforcement. With 5 days of consecutive enforcement a time halo of at least 6 days was noted. At the site of speed limit enforcement the average speed was reduced to around the...
Speed cameras for the prevention of road traffic injuries and deaths (2010) · Cochrane
no estimate extractedNRHigh
Intervention NR
2.8 km/h reduction in mean speed at monitoring site, 2km from experimental site.
Speed cameras for the prevention of road traffic injuries and deaths (2010) · Cochrane
no estimate extractedNRModerate
Intervention NR
Reductions in median speed by 40 km/h and 28km/h in left and middle car lanes and 23km/h in truck lane on autobahn, sustained through 10 years of continuous enforcement. Also reductions in 85th percentile speeds of 42 and 37km/h in car lanes and 3...
Speed cameras for the prevention of road traffic injuries and deaths (2010) · Cochrane
no estimate extractedNRLow
Intervention NR
During pilot program an overall 2.4 km/h reduction in mean speed with only small differences between the 3 cities. A 10.4% reduction in proportion of drivers exceeding the speed limit and a 4.5% reduction in those exceeding the speed limit by 10km.
Speed cameras for the prevention of road traffic injuries and deaths (2010) · Cochrane
no estimate extractedNRLow
Intervention NR
On 80 km/h sections an 8% reduction of speeding vehicles seen on experimental sites compared to control sites in year 1, with a further 2% decrease in year 2. On 100 km/h stretches a 5% reduction in number of speeders seen in year 1, with a furthe...
Speed cameras for the prevention of road traffic injuries and deaths (2010) · Cochrane
no estimate extractedNRLow
Intervention NR
Reduction in mean speeds by an average of 4.4 mph, 85% percentile speed reduction of 5.9 mph and a 35% reduction in percentage over the speed limit. These reductions were comparable for all monitored lengths e.g. up to 250m, 500m and 1 km.
Speed cameras for the prevention of road traffic injuries and deaths (2010) · Cochrane
no estimate extractedNRHigh
Intervention NR
65% reduction in speeding vehicles in excess of 15km/h or more, over the speed limit.
Speed cameras for the prevention of road traffic injuries and deaths (2010) · Cochrane
no estimate extractedNRLow
Intervention NR
Mean speed reduction of 4 km/h on experimental roads compared to 1.5 km/h on control roads. A 12% reduction in percentage of drivers over the allowed speed limit on experimental roads compared to 5% reduction on control roads.
Speed cameras for the prevention of road traffic injuries and deaths (2010) · Cochrane
no estimate extractedNRHigh
Intervention NR
Aggregation of data from the 4 roads in provinces (compared to phase 0) showed a reduction in average speed of 3km/h in phase 1 and 5km/h in phase 2, a reduction in 85 percentile speed of 3km/h in phase 1 and 8 km/h in phase 2. A reduction in prop...
Speed cameras for the prevention of road traffic injuries and deaths (2010) · Cochrane
no estimate extractedNRLow
Intervention NR
Reduction in average speeds by 0.9 to 4.8 km/h for all times of day reported. 10% reduction in proportion of speeding drivers. A time halo effect of up to 8 weeks was shown.
Speed cameras for the prevention of road traffic injuries and deaths (2010) · Cochrane
no estimate extractedNRHigh
Intervention NR
About 70% reduction in speeding vehicles when police present. A time halo effect lasted at least 2 days.
Speed cameras for the prevention of road traffic injuries and deaths (2010) · Cochrane
no estimate extractedNRLow
Intervention NR
Average reduction in mean speed 2.3 km/h (p = 0.05) at camera sites post 1st year. Average reduction in mean speeds 1.3 km/h (‐2.6 to 0.1)post 2nd year on experimental open roads
Speed cameras for the prevention of road traffic injuries and deaths (2010) · Cochrane
no estimate extractedNRModerate
Intervention NR
At the Scottsdale sites mean speeds decreased from 70 mph to about 65 mph. At the non‐Loop 101 sites (where no before data was available) mean speeds fluctuated between 68 and 69 mph. The proportion of vehicles in excess of the tolerated speed lim...
Speed cameras for the prevention of road traffic injuries and deaths (2010) · Cochrane
no estimate extractedNRModerate
Intervention NR
Mean speed at the 5 sites (where cameras were deployed) decreased by 10% (range 5% ‐18%) The proportion of drivers travelling > 10 mph above the speed limits declined by about 70% at locations with both warning signs and speed camera enforcement, ...
Speed cameras for the prevention of road traffic injuries and deaths (2010) · Cochrane
no estimate extractedNRModerate
Intervention NR
A 0.91mph significant reduction in mean speeds at experimental sites with a small insignificant reduction at control sites, 0.99mph significant reduction in 85th percentile speeds at experimental sites with a small insignificant reduction at contr...
Speed cameras for the prevention of road traffic injuries and deaths (2010) · Cochrane
no estimate extractedNRModerate
Intervention NR
A significant 14% reduction in mean speeds compared to control sites. The proportion of vehicles exceeding the speed limit by more than 10mph decreased by 82%.
Speed cameras for the prevention of road traffic injuries and deaths (2010) · Cochrane
no estimate extractedNRModerate
Intervention NR
23% crash reduction during the day and a 21% reduction at other times.
Speed cameras for the prevention of road traffic injuries and deaths (2010) · Cochrane
no estimate extractedNRHigh
Intervention NR
Aggregate changes in crashes showed an insignificant 19.7% reduction in all reported crashes with a 20.1% reduction in injury crashes and an 89.8% reduction in fatal crashes along camera segments.
Speed cameras for the prevention of road traffic injuries and deaths (2010) · Cochrane
no estimate extractedNRLow
Intervention NR
A significant 11% reduction in total crashes outside of city. Estimated 31% reduction in fatal crashes.
Speed cameras for the prevention of road traffic injuries and deaths (2010) · Cochrane
no estimate extractedNRLow
Intervention NR
Greatest crash reductions in areas within 2km of camera sites, with 31% (1100), 39% (2200), 19% (500) and 21% (1600) reductions estimated for hospitalisation, medically treated, other injury and non‐injury crashes respectively.
Speed cameras for the prevention of road traffic injuries and deaths (2010) · Cochrane
no estimate extractedNRHigh
Intervention NR
A significant 58% reduction in serious or fatal injury crashes.
Speed cameras for the prevention of road traffic injuries and deaths (2010) · Cochrane
no estimate extractedNRLow
Intervention NR
Overall mean speed reduction of about 2‐3km/h seen at both experimental and control sites. Distance halo of up to 14km downstream was seen. Time halo for at least the day after enforcement.
Speed cameras for the prevention of road traffic injuries and deaths (2010) · Cochrane
no estimate extractedNRHigh
Intervention NR
An estimated 7% reduction in overall injuries, 10% reduction in serious injury, and a 13% reduction in fatal crashes was reported
Speed cameras for the prevention of road traffic injuries and deaths (2010) · Cochrane
no estimate extractedNRHigh
Intervention NR
A net reduction of 71.3 % (p = 0.064) in injury crashes up to and including 4 days after the presence of enforcement. A net reduction of 73.9% (p =0.045) on the day when a mix of overt/covert enforcement employed.
Speed cameras for the prevention of road traffic injuries and deaths (2010) · Cochrane
no estimate extractedNRModerate
Intervention NR
A 25% reduction in expected crash rate, 11% reduction in injury crashes and a 17% reduction in daytime crash fatalities.
Speed cameras for the prevention of road traffic injuries and deaths (2010) · Cochrane
no estimate extractedNRLow
Intervention NR
A reduction of 16% (+/‐ 7%) in expected crashes along study corridor. A 2.8km/h reduction in mean speed at monitoring site.
Speed cameras for the prevention of road traffic injuries and deaths (2010) · Cochrane
no estimate extractedNRModerate
Intervention NR
Personal injury crash frequency reduced by a ratio of 1:1
Speed cameras for the prevention of road traffic injuries and deaths (2010) · Cochrane
no estimate extractedNRLow