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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Every word you type has to appear somewhere in the question, and the closest matches are ranked first.
75,239 questions in 5,342 reviews
current versionsNo studies 15,213 · 20.2%Ungraded 10,323 · 13.7%Very low 17,528 · 23.3%Low 17,951 · 23.9%Moderate 11,190 · 14.9%High 3,034 · 4%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Disc arthroplasty vs fusion Return to Work · patients with chronic low‐back pain Total disc replacement for chronic back pain in the presence of disc degeneration (2012) · Cochrane | no estimate extracted | 4 studies · 1188 participants | Very low |
Intervention NR Need for increased ventilatory assistance (invasive or non‐invasive) · individuals with an exacerbation of COPD Airway clearance techniques for chronic obstructive pulmonary disease (2012) · Cochrane | OR 0.21 [0.05, 0.85] | 4 studies · 171 participants | Low |
Intervention NR Duration of ventilatory assistance days · individuals with an exacerbation of COPD Airway clearance techniques for chronic obstructive pulmonary disease (2012) · Cochrane | no estimate extracted | 2 studies · 54 participants | Low |
Intervention NR Length of hospital stay days · individuals with an exacerbation of COPD Airway clearance techniques for chronic obstructive pulmonary disease (2012) · Cochrane | no estimate extracted | 3 studies · 171 participants | Low |
Intervention NR Depression remission · adults with diabetes mellitus and depression Psychological and pharmacological interventions for depression in patients with diabetes mellitus and… (2012) · Cochrane | OR 2.88 [1.58, 5.25] | 4 studies · 647 participants | Moderate |
Intervention NR Death from any cause · adults with diabetes mellitus and depression Psychological and pharmacological interventions for depression in patients with diabetes mellitus and… (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Health‐related quality of life · adults with diabetes mellitus and depression Psychological and pharmacological interventions for depression in patients with diabetes mellitus and… (2012) · Cochrane | no estimate extracted | 3 studies · 153 participants | Low |
Intervention NR Medication adherence/adverse effects · adults with diabetes mellitus and depression Psychological and pharmacological interventions for depression in patients with diabetes mellitus and… (2012) · Cochrane | no estimate extracted | 1 study · 28 participants | Low |
Intervention NR Metabolic control (HbA1c) [%] · adults with diabetes mellitus and depression Psychological and pharmacological interventions for depression in patients with diabetes mellitus and… (2012) · Cochrane | no estimate extracted | 5 studies · 238 participants | Moderate |
Intervention NR Healthcare costs · adults with diabetes mellitus and depression Psychological and pharmacological interventions for depression in patients with diabetes mellitus and… (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Diabetes complications · adults with diabetes mellitus and depression Psychological and pharmacological interventions for depression in patients with diabetes mellitus and… (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Death from any cause · adults with diabetes mellitus and depression Psychological and pharmacological interventions for depression in patients with diabetes mellitus and… (2012) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Health‐related quality of life · adults with diabetes mellitus and depression Psychological and pharmacological interventions for depression in patients with diabetes mellitus and… (2012) · Cochrane | no estimate extracted | 4 studies · 784 participants | Low |
Intervention NR Medication adherence/adverse effects · adults with diabetes mellitus and depression Psychological and pharmacological interventions for depression in patients with diabetes mellitus and… (2012) · Cochrane | no estimate extracted | 1 study · 291 participants | Low |
Intervention NR Glycaemic control (HbA1c) [%] · adults with diabetes mellitus and depression Psychological and pharmacological interventions for depression in patients with diabetes mellitus and… (2012) · Cochrane | no estimate extracted | 4 studies · 441 participants | Low |
Intervention NR Healthcare costs [annual costs and effects] · adults with diabetes mellitus and depression Psychological and pharmacological interventions for depression in patients with diabetes mellitus and… (2012) · Cochrane | no estimate extracted | 1 study · 208 participants | Low |
Intervention NR Depression remission · adults with diabetes mellitus and depression Psychological and pharmacological interventions for depression in patients with diabetes mellitus and… (2012) · Cochrane | OR 2.5 [1.21, 5.15] | 3 studies · 136 participants | Low |
Intervention NR Diabetes complications · adults with diabetes mellitus and depression Psychological and pharmacological interventions for depression in patients with diabetes mellitus and… (2012) · Cochrane | no estimate extracted | NR | No studies |
Curcumin vs placebo Relapse at 6 months Clinical Disease Activty Index more than 42 · Maintenance of remission in ulcerative colitis Curcumin for maintenance of remission in ulcerative colitis (2012) · Cochrane | RR 0.24 [0.05, 1.09] | 1 study · 89 participants | Low |
Curcumin vs placebo Relapse at 12 months Clinical Disease Activty Index more than 42 · Maintenance of remission in ulcerative colitis Curcumin for maintenance of remission in ulcerative colitis (2012) · Cochrane | RR 0.7 [0.35, 1.4] | 1 study · 89 participants | Low |
Curcumin vs placebo Clinical Activity Index at 6 months Clinical Disease Activty Index 2. Scale from: 0 to 12. · Maintenance of remission in ulcerative colitis Curcumin for maintenance of remission in ulcerative colitis (2012) · Cochrane | no estimate extracted | 1 study · 82 participants | Low |
Curcumin vs placebo Endoscopic Index at 6 months Endoscopic Index9. Scale from: 1 to 4. · Maintenance of remission in ulcerative colitis Curcumin for maintenance of remission in ulcerative colitis (2012) · Cochrane | no estimate extracted | 1 study · 82 participants | Low |
Intervention NR Overall QoL change score ‐ up to 12 weeks' · people who are undergoing active treatment for cancer Exercise interventions on health‐related quality of life for people with cancer during active treatment (2012) · Cochrane | no estimate extracted | 11 studies · 806 participants | Very low |
Intervention NR Overall physical function change score ‐ 6 months' · people who are undergoing active treatment for cancer Exercise interventions on health‐related quality of life for people with cancer during active treatment (2012) · Cochrane | no estimate extracted | 4 studies · 305 participants | Very low |
Intervention NR Overall role function change score ‐ up to 12 weeks' · people who are undergoing active treatment for cancer Exercise interventions on health‐related quality of life for people with cancer during active treatment (2012) · Cochrane | no estimate extracted | 7 studies · 437 participants | Very low |
Intervention NR Overall role function · people who are undergoing active treatment for cancer Exercise interventions on health‐related quality of life for people with cancer during active treatment (2012) · Cochrane | no estimate extracted | 15 studies · 1100 participants | Low |
Intervention NR Overall social function change score ‐ up to 12 weeks' · people who are undergoing active treatment for cancer Exercise interventions on health‐related quality of life for people with cancer during active treatment (2012) · Cochrane | no estimate extracted | 5 studies · 378 participants | Very low |
Intervention NR Overall social function · people who are undergoing active treatment for cancer Exercise interventions on health‐related quality of life for people with cancer during active treatment (2012) · Cochrane | no estimate extracted | 16 studies · 1164 participants | Low |
Intervention NR Overall QoL · people who are undergoing active treatment for cancer Exercise interventions on health‐related quality of life for people with cancer during active treatment (2012) · Cochrane | no estimate extracted | 20 studies · 1166 participants | Very low |
Intervention NR Overall anxiety · people who are undergoing active treatment for cancer Exercise interventions on health‐related quality of life for people with cancer during active treatment (2012) · Cochrane | no estimate extracted | 12 studies · 1010 participants | Very low |
Intervention NR Overall anxiety · people who are undergoing active treatment for cancer Exercise interventions on health‐related quality of life for people with cancer during active treatment (2012) · Cochrane | no estimate extracted | 3 studies · 286 participants | Low |
Intervention NR Overall depression · people who are undergoing active treatment for cancer Exercise interventions on health‐related quality of life for people with cancer during active treatment (2012) · Cochrane | no estimate extracted | 15 studies · 1250 participants | Very low |
Intervention NR Overall depression · people who are undergoing active treatment for cancer Exercise interventions on health‐related quality of life for people with cancer during active treatment (2012) · Cochrane | no estimate extracted | 4 studies · 452 participants | Low |
Intervention NR Overall fatigue change score ‐ up to 12 weeks' · people who are undergoing active treatment for cancer Exercise interventions on health‐related quality of life for people with cancer during active treatment (2012) · Cochrane | no estimate extracted | 12 studies · 971 participants | Very low |
Intervention NR Overall fatigue · people who are undergoing active treatment for cancer Exercise interventions on health‐related quality of life for people with cancer during active treatment (2012) · Cochrane | no estimate extracted | 23 studies · 1721 participants | Very low |
Intervention NR Overall physical function change score ‐ up to 12 weeks' · people who are undergoing active treatment for cancer Exercise interventions on health‐related quality of life for people with cancer during active treatment (2012) · Cochrane | no estimate extracted | 8 studies · 540 participants | Very low |
Intervention NR Social Competence · People aged 6 to 21 with ASD Social skills groups for people aged 6 to 21 with autism spectrum disorders (ASD) (2012) · Cochrane | no estimate extracted | 4 studies · 178 participants | Low |
Intervention NR Social Communication Comprehensive Assessment of Spoken Language · People aged 6 to 21 with ASD Social skills groups for people aged 6 to 21 with autism spectrum disorders (ASD) (2012) · Cochrane | no estimate extracted | 1 study · 34 participants | Low |
Intervention NR Emotion Recognition Diagnostic Analysis of Nonverbal Accuracy‐2: Child Faces · People aged 6 to 21 with ASD Social skills groups for people aged 6 to 21 with autism spectrum disorders (ASD) (2012) · Cochrane | no estimate extracted | 2 studies · 54 participants | Low |
Intervention NR Friendship Piers‐Harris Self‐Concept Scale or Friendship Qualities Scale · People aged 6 to 21 with ASD Social skills groups for people aged 6 to 21 with autism spectrum disorders (ASD) (2012) · Cochrane | no estimate extracted | 2 studies · 101 participants | Low |
Intervention NR Loneliness Loneliness Scale · People aged 6 to 21 with ASD Social skills groups for people aged 6 to 21 with autism spectrum disorders (ASD) (2012) · Cochrane | no estimate extracted | 1 study · 68 participants | Low |
Intervention NR Child Depression Beck Depression Index · People aged 6 to 21 with ASD Social skills groups for people aged 6 to 21 with autism spectrum disorders (ASD) (2012) · Cochrane | no estimate extracted | 1 study · 18 participants | Low |
Intervention NR Maternal Depression Beck Depression Index · People aged 6 to 21 with ASD Social skills groups for people aged 6 to 21 with autism spectrum disorders (ASD) (2012) · Cochrane | no estimate extracted | 1 study · 18 participants | Low |
Extended peginterferon plus ribavirin treatment for 72 weeks vs standard peginterferon plus ribavirin treatment Sustained virological response (SVR) · participants with detectable HCV RNA after 12 weeks of treatment with pegylated interferon and ribavirin, but with >=… Extended peginterferon plus ribavirin treatment for 72 weeks versus standard peginterferon plus ribavirin… (2012) · Cochrane | RR 1.43 | 5 studies · 411 participants | Very low |
Extended peginterferon plus ribavirin treatment for 72 weeks vs standard peginterferon plus ribavirin treatment Relapse · participants with detectable HCV RNA after 12 weeks of treatment with pegylated interferon and ribavirin, but with >=… Extended peginterferon plus ribavirin treatment for 72 weeks versus standard peginterferon plus ribavirin… (2012) · Cochrane | RR 0.59 | 3 studies · 175 participants | Very low |
Extended peginterferon plus ribavirin treatment for 72 weeks vs standard peginterferon plus ribavirin treatment End of treatment response (ETR) · participants with detectable HCV RNA after 12 weeks of treatment with pegylated interferon and ribavirin, but with >=… Extended peginterferon plus ribavirin treatment for 72 weeks versus standard peginterferon plus ribavirin… (2012) · Cochrane | RR 0.96 | 3 studies · 334 participants | Very low |
Extended peginterferon plus ribavirin treatment for 72 weeks vs standard peginterferon plus ribavirin treatment Sustained virological response (SVR) · participants with detectable HCV RNA after four weeks of treatment with pegylated interferon and ribavirin Extended peginterferon plus ribavirin treatment for 72 weeks versus standard peginterferon plus ribavirin… (2012) · Cochrane | RR 1.27 | 3 studies · 995 participants | Low |
Extended peginterferon plus ribavirin treatment for 72 weeks vs standard peginterferon plus ribavirin treatment Relapse rate · participants with detectable HCV RNA after four weeks of treatment with pegylated interferon and ribavirin Extended peginterferon plus ribavirin treatment for 72 weeks versus standard peginterferon plus ribavirin… (2012) · Cochrane | RR 0.59 | 3 studies · 703 participants | Low |
Extended peginterferon plus ribavirin treatment for 72 weeks vs standard peginterferon plus ribavirin treatment End of treatment response (ETR) · participants with detectable HCV RNA after four weeks of treatment with pegylated interferon and ribavirin Extended peginterferon plus ribavirin treatment for 72 weeks versus standard peginterferon plus ribavirin… (2012) · Cochrane | RR 0.99 | 3 studies · 995 participants | Low |
Extended peginterferon plus ribavirin treatment for 72 weeks vs standard peginterferon plus ribavirin treatment Adherance to treatment · participants with detectable HCV RNA after four weeks of treatment with pegylated interferon and ribavirin or… Extended peginterferon plus ribavirin treatment for 72 weeks versus standard peginterferon plus ribavirin… (2012) · Cochrane | RR 0.95 | 2 studies · 260 participants | Moderate |