Cochrane · systematic review · CD008326

Total disc replacement for chronic back pain in the presence of disc degeneration

Jacobs, W, Van der Gaag, NA, Tuschel, A, et al. · Cochrane Database of Systematic Reviews · 2012 · Cochrane Library

Back and NeckAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
10
current version
GRADE rated
8
No studies
2
Included studies
NR
No studies 2 · 20%Ungraded 0 · 0%Very low 4 · 40%Low 2 · 20%Moderate 2 · 20%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Disc arthroplasty versus fusion for chronic low‐back pain

Population: patients with chronic low‐back pain
10 questions
OutcomeEffectEvidenceStatus / GRADE
Improvement in Back Pain VAS 100 mm scale
Disc arthroplasty vs fusion
no estimate extracted2 studies · 676 participantsLow
Downgraded: imprecision, publication bias
Patient satisfaction Questionnaire
Disc arthroplasty vs fusion
OR 1.93 [1.36, 2.76]4 studies · 958 participantsModerate
Downgraded: imprecision, inconsistency, publication bias
Improvement in function Oswestry score. Scale from: ‐100 to 100.
Disc arthroplasty vs fusion
no estimate extracted5 studies · 1207 participantsModerate
Downgraded: imprecision, inconsistency, publication bias
Percentage of patients improved on function Oswestry score
Disc arthroplasty vs fusion
OR 1.45 [1.06, 1.98]5 studies · 1244 participantsLow
Downgraded: imprecision, inconsistency, publication bias
Disability Roland Morris
Disc arthroplasty vs fusion
no estimate extractedNRNo studies
Physical and mental health SF‐36, SF‐12
Disc arthroplasty vs fusion
no estimate extracted2 studies · 863 participantsVery low
Downgraded: imprecision, inconsistency, publication bias
Economic status Euro‐QoL; EQ‐5D
Disc arthroplasty vs fusion
no estimate extracted1 study · 152 participantsVery low
Downgraded: imprecision, inconsistency, publication bias
Daily activity
Disc arthroplasty vs fusion
no estimate extractedNRNo studies
Return to Work
Disc arthroplasty vs fusion
no estimate extracted4 studies · 1188 participantsVery low
Downgraded: imprecision, inconsistency, publication bias
Adverse Effects
Disc arthroplasty vs fusion
no estimate extractedNRVery low
Downgraded: imprecision, inconsistency, publication bias