Findings

What do systematic reviews say?

3,696 questions · 3,815 findings · 855 reviews

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No studies found 573 · 15%GRADE not reported 374 · 9.8%Very low 993 · 26%Low 1,062 · 27.8%Moderate 614 · 16.1%High 199 · 5.2%

Intervention not reported

LDL‐Cholesterol rosuvastatin 40 mg/day · participantswith normal or abnormal lipid profiles

1 finding from 1 review

Rosuvastatin for lowering lipids 2014 · Cochrane Headline outcomes only
no estimate extracted
18 studies · 3512 participants
High

Intervention not reported

Cough‐free days Percentage of days free of cough · 18 to 80 years of age with bronchiectasis

The intervention may leads to higher cough‐free days Percentage of days free of cough (low certainty).

1 finding from 1 review

Combination inhaled corticosteroids and long‐acting beta₂‐agonists for children and adults with bronchiectasis 2014 · Cochrane Headline outcomes only
MD 12.3 [2.38, 22.22]
1 study · 40 participants
Low

Supplementary box model training vs standard training

Proportion with day surgery · surgical trainees with limited prior laparoscopic experience

1 finding from 1 review

Laparoscopic surgical box model training for surgical trainees with limited prior laparoscopic experience 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Low

Intervention not reported

Length of hospital stay (days) · adults with acute asthma

1 finding from 1 review

Intravenous magnesium sulfate for treating adults with acute asthma in the emergency department 2014 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 949 participants
Low

Dihydroartemisinin‐piperaquine vs artemether‐lumefantrine (AL)

Treatment failure Day 28 · adults and children with uncomplicated P falciparum malaria

Dihydroartemisinin‐piperaquine leads to lower treatment failure Day 28 compared with artemether‐lumefantrine (high certainty).

1 finding from 1 review

Dihydroartemisinin‐piperaquine for treating uncomplicated Plasmodium falciparum malaria 2014 · Cochrane Headline outcomes only
RR 0.34 [0.3, 0.39]
9 studies · 6200 participants
High

Dihydroartemisinin‐piperaquine vs artemether‐lumefantrine (AL)

Treatment failure Day 63 · adults and children with uncomplicated P falciparum malaria

Dihydroartemisinin‐piperaquine leads to lower treatment failure Day 63 compared with artemether‐lumefantrine (high certainty).

1 finding from 1 review

Dihydroartemisinin‐piperaquine for treating uncomplicated Plasmodium falciparum malaria 2014 · Cochrane Headline outcomes only
RR 0.71 [0.65, 0.78]
2 studies · 3200 participants
High

Antibiotics vs antibiotics during postpartum period

Length of treatment · women with management of intra‐amniotic infection

1 finding from 1 review

Antibiotic regimens for management of intra‐amniotic infection 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 131 participants
Very low

Antibiotics (short duration) vs antibiotics (long duration) postpartum

Length of hospital stay · women with management of intra‐amniotic infection

1 finding from 1 review

Antibiotic regimens for management of intra‐amniotic infection 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 292 participants
Moderate

Intrapartum vs postpartum treatment

Maternal postpartum hospital stay (days) · women with management of intra‐amniotic infection

1 finding from 1 review

Antibiotic regimens for management of intra‐amniotic infection 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 45 participants
Very low

Antibiotics vs antibiotics alone

Maternal postpartum hospital stay (days) · women in labor with management of intra‐amniotic infection

1 finding from 1 review

Antibiotic regimens for management of intra‐amniotic infection 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 125 participants
Low

Combination of manual therapy, exercise, electrotherapy and oral NSAID vs oral NSAID

Global assessment of treatment success · patients with adhesive capsulitis (frozen shoulder)

Combination of manual therapy, exercise, electrotherapy and oral NSAID may leads to higher global assessment of treatment success "Disappearance of shoulder… compared with oral NSAID (low certainty).

1 finding from 1 review

Manual therapy and exercise for adhesive capsulitis (frozen shoulder) 2014 · Cochrane Headline outcomes only
RR 1.45
1 study · 109 participants
Low

An extended NVP regimen administered to infants for 6 weeks vs sdNVP

HIV Transmission at 6 months among those whose HIV diagnostic testing was negative within 7 days of birth · Breastfeeding infants of HIV‐infected mothers

An extended NVP regimen administered to infants for 6 weeks showed no clear difference in HIV Transmission at 6 months among those whose HIV diagnostic… compared with sdNVP (moderate certainty).

1 finding from 1 review

Antiretroviral interventions for preventing breast milk transmission of HIV 2014 · Cochrane Headline outcomes only
RR 0.78 [0.57, 1.07]
1 study · 1887 participants
Moderate

An extended NVP regimen administered to infants for 6 weeks vs sdNVP

Infant Mortality at 6 months among those whose HIV diagnostic testing was negative within 7 days of birth · Breastfeeding infants of HIV‐infected mothers

An extended NVP regimen administered to infants for 6 weeks may leads to lower infant Mortality at 6 months among those whose HIV diagnostic… compared with sdNVP (low certainty).

1 finding from 1 review

Antiretroviral interventions for preventing breast milk transmission of HIV 2014 · Cochrane Headline outcomes only
RR 0.47 [0.26, 0.84]
1 study · 1887 participants
Low

An extended NVP regimen administered to infants for 6 weeks vs sdNVP

HIV Transmission or Death at 6 months among those whose HIV diagnostic testing was negative within 7 days of birth · Breastfeeding infants of HIV‐infected mothers

An extended NVP regimen administered to infants for 6 weeks probably leads to lower HIV Transmission or Death at 6 months among those whose HIV… compared with sdNVP (moderate certainty).

1 finding from 1 review

Antiretroviral interventions for preventing breast milk transmission of HIV 2014 · Cochrane Headline outcomes only
RR 0.72 [0.54, 0.95]
1 study · 1887 participants
Moderate

An extended NVP regimen administered to infants for 6 weeks vs sdNVP

HIV Transmission at 12 months among those whose HIV diagnostic testing was negative within 7 days of birth · Breastfeeding infants of HIV‐infected mothers

An extended NVP regimen administered to infants for 6 weeks showed no clear difference in HIV Transmission at 12 months among those whose HIV diagnostic… compared with sdNVP (moderate certainty).

1 finding from 1 review

Antiretroviral interventions for preventing breast milk transmission of HIV 2014 · Cochrane Headline outcomes only
RR 0.89 [0.67, 1.17]
1 study · 1813 participants
Moderate

An extended NVP regimen administered to infants for 6 weeks vs sdNVP

Infant Mortality at 12 months among those whose HIV diagnostic testing was negative within 7 days of birth · Breastfeeding infants of HIV‐infected mothers

An extended NVP regimen administered to infants for 6 weeks probably leads to lower infant Mortality at 12 months among those whose HIV diagnostic… compared with sdNVP (moderate certainty).

1 finding from 1 review

Antiretroviral interventions for preventing breast milk transmission of HIV 2014 · Cochrane Headline outcomes only
RR 0.53 [0.32, 0.85]
1 study · 2350 participants
Moderate

An extended NVP regimen administered to infants for 6 weeks vs sdNVP

HIV Transmission or Death at 12 months among those whose HIV diagnostic testing was negative within 7 days of birth · Breastfeeding infants of HIV‐infected mothers

An extended NVP regimen administered to infants for 6 weeks showed no clear difference in HIV Transmission or Death at 12 months among those whose HIV… compared with sdNVP (moderate certainty).

1 finding from 1 review

Antiretroviral interventions for preventing breast milk transmission of HIV 2014 · Cochrane Headline outcomes only
RR 0.79 [0.61, 1.01]
1 study · 1883 participants
Moderate

Transbuccal miniplate combined with intraoral approach vs Intraoral approach alone

Requirement for additional (surgical) interventions (plate removal within 90 days) · Adults with fractures of the mandibular angle

Transbuccal miniplate combined with intraoral approach led to lower requirement for additional (surgical) interventions (plate removal… compared with intraoral approach alone; GRADE not reported.

1 finding from 1 review

Interventions for the management of mandibular fractures 2013 · Cochrane All outcomes
90 days · Angle of mandible only
RR 0.57 [0.33, 0.98]
1 study · 140 participants
GRADE not reported

Intervention not reported

Duration of cold symptoms (days) · patients with common cold

1 finding from 1 review

Zinc for the common cold 2013 · Cochrane Headline outcomes only
no estimate extracted
14 studies · 1656 participants
Low

Intervention not reported

Number of participants symptomatic after 7 days of treatment · patients with common cold

It is very uncertain whether the intervention changes number of participants symptomatic after 7 days of treatment (very low certainty).

1 finding from 1 review

Zinc for the common cold 2013 · Cochrane Headline outcomes only
OR 0.45 [0.2, 1]
5 studies · 476 participants
Very low