evidence/gaps
Cochrane · systematic review · CD001364

Zinc for the common cold

Singh Meenu, Das Rashmi R · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library

Acute Respiratory Infections2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 1 · 14.3%Very low 3 · 42.9%Low 3 · 42.9%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Show all 2 versions

Comparison

Population: patients with common cold
7 questions
OutcomeEffectEvidenceStatus / GRADE
Duration of cold symptoms (days)
no estimate extracted14 studies · 1656 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias
Severity of symptom score
no estimate extracted5 studies · 513 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias
Incidence of common cold
RR 0.64 [0.47, 0.88]2 studies · 394 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias
Number of participants symptomatic after 7 days of treatment
OR 0.45 [0.2, 1]5 studies · 476 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias
School absence (number of days)
no estimate extracted2 studies · 394 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias
Antibiotic use
OR 0.27 [0.16, 0.46]2 studies · 394 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias
Any adverse event
OR 1.58 [1.19, 2.09]8 studies · 1217 participantsUngraded