Cochrane · systematic review · CD001364
Zinc for the common cold
Singh Meenu, Das Rashmi R · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 1 · 14.3%Very low 3 · 42.9%Low 3 · 42.9%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyComparison
Population: patients with common cold
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Duration of cold symptoms (days) | no estimate extracted | 14 studies · 1656 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias |
Severity of symptom score | no estimate extracted | 5 studies · 513 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias |
Incidence of common cold | RR 0.64 [0.47, 0.88] | 2 studies · 394 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias |
Number of participants symptomatic after 7 days of treatment | OR 0.45 [0.2, 1] | 5 studies · 476 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias |
School absence (number of days) | no estimate extracted | 2 studies · 394 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias |
Antibiotic use | OR 0.27 [0.16, 0.46] | 2 studies · 394 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias |
Any adverse event | OR 1.58 [1.19, 2.09] | 8 studies · 1217 participants | Ungraded |
Comparison
Population: patients with common cold
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Duration of cold symptoms (days) | no estimate extracted | 6 studies · 762 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Severity of symptom score | no estimate extracted | 5 studies · 513 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Incidence of common cold | RR 0.64 [0.47, 0.88] | 2 studies · 394 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Number of participants symptomatic after 7 days of treatment | OR 0.45 [0.2, 1] | 5 studies · 476 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
School absenteeism (number of days) | no estimate extracted | 2 studies · 394 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Antibiotic use | RR 0.27 [0.16, 0.46] | 2 studies · 394 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Any adverse event | RR 1.59 [0.97, 2.58] | 5 studies · 796 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency, indirectness |