Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

394 questions · 412 findings · 112 reviews

No studies found 51 · 12.4%GRADE not reported 41 · 10%Very low 86 · 20.9%Low 121 · 29.4%Moderate 84 · 20.4%High 29 · 7%

Regional (spinal, epidural, caudal) vs general anaesthesia

Any oxygen desaturation occurring 12‐24 hours following completion of the operation · Preterm infants requiring surgery for inguinal hernia in early infancy

Regional (spinal, epidural, caudal) showed no clear difference in any oxygen desaturation occurring 12‐24 hours following completion… compared with general anaesthesia (moderate certainty).

1 finding from 1 review

Bovine lung lavage surfactant extract vs modified bovine minced lung surfactant extract

Death or oxygen requirement at 36 weeks' postmenstrual age · Preterm infants for treatment of RDS

Bovine lung lavage surfactant extract showed no clear difference in death or oxygen requirement at 36 weeks' postmenstrual age compared with modified bovine minced lung surfactant extract (high certainty).

1 finding from 1 review

Bovine lung lavage surfactant extract vs porcine minced lung surfactant extract

Oxygen requirement at 36 weeks' postmenstrual age · Preterm infants for treatment of RDS

Bovine lung lavage surfactant extract showed no clear difference in oxygen requirement at 36 weeks' postmenstrual age compared with porcine minced lung surfactant extract (low certainty).

1 finding from 1 review

Bovine lung lavage surfactant extract vs modified bovine minced lung surfactant extract

Oxygen requirement at 36 weeks' postmenstrual age · Preterm infants for prevention of RDS

Bovine lung lavage surfactant extract showed no clear difference in oxygen requirement at 36 weeks' postmenstrual age compared with modified bovine minced lung surfactant extract (moderate certainty).

1 finding from 1 review

Modified bovine minced lung surfactant extract vs porcine minced lung surfactant extract

Oxygen requirement at 36 weeks' postmenstrual age · Preterm infants for treatment of RDS

Modified bovine minced lung surfactant extract showed no clear difference in oxygen requirement at 36 weeks' postmenstrual age compared with porcine minced lung surfactant extract (moderate certainty).

1 finding from 1 review

Modified bovine minced lung surfactant extract vs porcine minced lung surfactant extract

Death or oxygen requirement at 36 weeks' postmenstrual age · Preterm infants for treatment of RDS

Modified bovine minced lung surfactant extract probably leads to higher death or oxygen requirement at 36 weeks' postmenstrual age compared with porcine minced lung surfactant extract (moderate certainty).

1 finding from 1 review

Bovine lung lavage surfactant extract vs modified bovine minced lung surfactant extract

Death or oxygen requirement at 36 weeks' postmenstrual age · Preterm infants for prevention of RDS

Bovine lung lavage surfactant extract showed no clear difference in death or oxygen requirement at 36 weeks' postmenstrual age compared with modified bovine minced lung surfactant extract (high certainty).

1 finding from 1 review

Bovine lung lavage surfactant extract vs modified bovine minced lung surfactant extract

Oxygen requirement at 36 weeks' postmenstrual age · Preterm infants for treatment of RDS

Bovine lung lavage surfactant extract showed no clear difference in oxygen requirement at 36 weeks' postmenstrual age (all infants) compared with modified bovine minced lung surfactant extract (high certainty).

1 finding from 1 review