Cochrane · systematic review · CD011090
Effects of opioid, hypnotic and sedating medications on sleep‐disordered breathing in adults with obstructive sleep apnoea
Mason, M, Cates, CJ, Smith, I · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
AirwaysAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 100%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison
Population: participants with sleep apnoea prescribed sedatives, hypnotics (including benzodiazepines (BZDs), non‐BZD GABAA receptor agonists ('Z drugs'), sodium oxybate (SXB), melatonin agonists) and opioids
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Apnoea‐ hypopnoea index (AHI) (events/h) | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision |
Oxygen desaturation index (ODI) | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision |
Fall in minimum SpO2 | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision |