Cochrane · systematic review · CD009419

Neuromuscular electrical stimulation for muscle weakness in adults with advanced disease

Jones, S, Man, WDC, Gao, W, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 33.3%Low 2 · 33.3%Moderate 2 · 33.3%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Neuromuscular electrical stimulation (NMES) versus control for adults with advanced disease for muscle weakness

Population: adults with advanced disease for muscle weakness
6 questions
OutcomeEffectEvidenceStatus / GRADE
Quadriceps muscle strength Handheld or fixed dynamometry
Neuromuscular electrical stimulation (NMES) vs control
no estimate extracted12 studies · 781 participantsLow
Downgraded: inconsistency
Safety Serious adverse events
Neuromuscular electrical stimulation (NMES) vs control
no estimate extracted18 studies · 933 participantsModerate
Downgraded: risk of bias
Safety Adverse events: Muscle discomfort
Neuromuscular electrical stimulation (NMES) vs control
no estimate extracted18 studies · 933 participantsModerate
Downgraded: risk of bias
Muscle mass Anthropometry, DEXA, ultrasound, computed tomography
Neuromuscular electrical stimulation (NMES) vs control
no estimate extracted8 studies · 314 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Exercise performance ‐ walking distance 6MWT, ISWT, ESWT
Neuromuscular electrical stimulation (NMES) vs control
no estimate extracted13 studies · 788 participantsVery low
Downgraded: risk of bias, inconsistency
Exercise performance ‐ peak oxygen uptake
Neuromuscular electrical stimulation (NMES) vs control
no estimate extracted4 studies · 109 participantsLow
Downgraded: risk of bias, inconsistency