Question · asked by 1 review

Bovine lung lavage surfactant extract vs modified bovine minced lung surfactant extract: Death or oxygen requirement at 36 weeks' postmenstrual age

Bovine lung lavage surfactant extract showed no clear difference in death or oxygen requirement at 36 weeks' postmenstrual age compared with modified bovine minced lung surfactant extract (high certainty).

What each review found

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FindingEffectStudiesGRADE certainty
Bovine lung lavage surfactant extract vs modified bovine minced lung surfactant extract
Death or oxygen requirement at 36 weeks' postmenstrual age · Preterm infants for treatment of RDS
Bovine lung lavage surfactant extract showed no clear difference in death or oxygen requirement at 36 weeks' postmenstrual age compared with modified bovine minced lung surfactant extract (high certainty).
Comparison of animal‐derived surfactants for the prevention and treatment of respiratory distress syndrome… (2015) · Cochrane Headline outcomes only
RR 0.95 [0.86, 1.06]3 studies · 2009 participantsHigh

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Comparison of animal‐derived surfactants for the prevention and treatment of respiratory distress syndrome in preterm infants
2015 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.