Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,696 questions · 3,815 findings · 855 reviews

No studies found 573 · 15%GRADE not reported 374 · 9.8%Very low 993 · 26%Low 1,062 · 27.8%Moderate 614 · 16.1%High 199 · 5.2%

Mesalamine vs sulfasalazine

Clinical remission or improvement · patients with Induction of remission or response in Crohn's disease

It is very uncertain whether mesalamine changes induction of remission (CDAI < 150) or clinical improvement ‐… compared with sulfasalazine (alone or (very low certainty).

2 findings from 1 review

Simethicone vs placebo

Reduction in crying duration Difference between final values (hours per day of crying) · infants with colic defined by recognised criteria

It is very uncertain whether simethicone changes reduction in crying duration Difference between final values (hours… compared with placebo (very low certainty).

1 finding from 1 review

Herbal agents vs placebo

Reduction in crying duration Difference before and after treatment (hours per day of crying) · patients with infantile colic

Herbal agents may leads to higher reduction in crying duration Difference before and after treatment… compared with placebo (low certainty).

1 finding from 1 review

Sugar vs placebo

Reduction in crying duration Difference before and after treatment (hours per day of crying) · infants with colic defined by recognised criteria

It is very uncertain whether sugar changes reduction in crying duration Difference before and after treatment… compared with placebo (very low certainty).

1 finding from 1 review