Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

3,696 questions · 3,815 findings · 855 reviews

No studies found 573 · 15%GRADE not reported 374 · 9.8%Very low 993 · 26%Low 1,062 · 27.8%Moderate 614 · 16.1%High 199 · 5.2%

Oral + inhaled dual therapy vs oral monotherapy

Serious adverse events. Outcome assessed on day 42 · bronchiectasis

It is very uncertain whether oral + inhaled dual therapy changes serious adverse events. Outcome assessed on day 42 compared with oral monotherapy (very low certainty).

1 finding from 1 review

Oral + inhaled dual therapy vs oral monotherapy

Microbiological response: eradicated. Outcome assessed on day 21 · bronchiectasis

It is very uncertain whether oral + inhaled dual therapy changes microbiological response: eradicated. Outcome assessed on day 21 compared with oral monotherapy (very low certainty).

1 finding from 1 review

Continuation vs discontinuation of antiplatelet therapy

All‐cause mortality (up to 30 days) · adults undergoing non‐cardiac surgery

Continuation showed no clear difference in all‐cause mortality (up to 30 days) compared with discontinuation of antiplatelet therapy (low certainty).

1 finding from 1 review

Continuation vs discontinuation of antiplatelet therapy

Ischaemic events: peripheral thrombosis, cerebral myocardial infarction (within 30 days of surgery) · adults undergoing non‐cardiac surgery

Continuation showed no clear difference in ischaemic events: peripheral thrombosis, cerebral myocardial… compared with discontinuation of antiplatelet therapy (low certainty).

1 finding from 1 review

Intramuscular corticosteroids vs oral corticosteroid

Relapse · patients with acute asthma

Intramuscular corticosteroids showed no clear difference in relapse within 10 days post‐discharge compared with oral corticosteroids (moderate certainty).

2 findings from 1 review

Prophylactic platelet transfusion prior to surgery vs no prophylactic platelet transfusion prior to surgery

All‐cause mortality within 30 days of surgery · people with a low platelet count

It is very uncertain whether prophylactic platelet transfusion prior to surgery changes all‐cause mortality within 30 days of surgery compared with no prophylactic platelet transfusion prior to surgery (very low certainty).

1 finding from 1 review

Prophylactic platelet transfusion prior to surgery vs alternative treatment

Number of participants with minor procedure‐related bleeding within 7 days of surgery · people with a low platelet count

It is very uncertain whether prophylactic platelet transfusion prior to surgery changes number of participants with minor procedure‐related bleeding within… compared with alternative treatments (very low certainty).

1 finding from 1 review